3-甲基-2-(3-甲基-2-丁烯-1-基)-2-环戊烯-1-酮合成路线 （共 14 条）
反应条件
1: 70 percent / O3 / CH2Cl2 / -78 °C 2: 1.) n-BuLi / 1.) THF-hexane, RT, 1 h, 2.) THF, -10 deg C, 1.5 h View Scheme
参考文献
Armstead, David A.; Mann, John
Synthetic Communications, 1985 , vol. 15, # 13 p. 1147 - 1152
反应条件
sodium hydroxide; Aliquatreg; 336 in water; toluene
T=100°C; 4 h;
参考文献
International Flavors and Fragrances Inc.
Patent: US7141699 B1, 2006 ;
Location in patent: Page/Page column 5 ;
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in hexane; water
24 h; Ambient temperature;
参考文献
Armstead, David A.; Mann, John
Synthetic Communications, 1985 , vol. 15, # 13 p. 1147 - 1152
反应条件
2: 1.) LDA, 3.) Cu(OAc)2
3: 70 percent / pyridinium chlorochromate
4: 70 percent / 2M NaOH, Bu4NHSO4 / hexane; H2O / 24 h / Ambient temperature
View Scheme
参考文献
Armstead, David A.; Mann, John
Synthetic Communications, 1985 , vol. 15, # 13 p. 1147 - 1152
反应条件
1: 1.) LDA, 3.) Cu(OAc)2
2: 70 percent / pyridinium chlorochromate
3: 70 percent / 2M NaOH, Bu4NHSO4 / hexane; H2O / 24 h / Ambient temperature
View Scheme
参考文献
Armstead, David A.; Mann, John
Synthetic Communications, 1985 , vol. 15, # 13 p. 1147 - 1152
反应条件
1: 70 percent / pyridinium chlorochromate
2: 70 percent / 2M NaOH, Bu4NHSO4 / hexane; H2O / 24 h / Ambient temperature
View Scheme
参考文献
Armstead, David A.; Mann, John
Synthetic Communications, 1985 , vol. 15, # 13 p. 1147 - 1152
参考文献
LaLonde,R.T. et al.
Journal of Organic Chemistry, 1977 , vol. 42, p. 2113 - 2118
参考文献
Mathew, Jacob
Journal of Organic Chemistry, 1990 , vol. 55, # 18 p. 5294 - 5297
反应条件
1: 1.) KN(TMS)2 / 2.) HMPA
2: 34 percent
3: Raney nickel
View Scheme
参考文献
Mathew, Jacob
Journal of Organic Chemistry, 1990 , vol. 55, # 18 p. 5294 - 5297
反应条件
1: 34 percent
2: Raney nickel
View Scheme
参考文献
Mathew, Jacob
Journal of Organic Chemistry, 1990 , vol. 55, # 18 p. 5294 - 5297
