2-氯-5-硝基苯酚合成路线

619-10-32-氯-5-硝基苯酚

31185-45-2

参考文献

Baker,B.R.; Ashton,W.T.
Journal of Medicinal Chemistry, 1970 , vol. 13, # 6 p. 1149 - 1154

619-10-32-氯-5-硝基苯酚

31185-43-0

参考文献

Baker,B.R.; Ashton,W.T.
Journal of Medicinal Chemistry, 1970 , vol. 13, # 6 p. 1149 - 1154

619-10-32-氯-5-硝基苯酚+

106-93-4二溴乙烷

3062-53-12-(2-溴乙氧基)-1-氯-4-硝基苯

参考文献

Wu, Chengde; Anderson, C. Eric; Bui, Huong; Dupre, Brian; Gao, Daxin; Holland, George W.; Kassir, Jamal; Li, Wen; Wang, Junmei
Patent: US2005/54850 A1, 2005 ;

619-10-32-氯-5-硝基苯酚+

107-04-01-溴-2-氯乙烷

769961-20-8+

3062-53-12-(2-溴乙氧基)-1-氯-4-硝基苯

参考文献

Potashman, Michele H.; Bready, James; Coxon, Angela; Demelfi Jr., Thomas M.; DiPietro, Lucian; Doerr, Nicholas; Elbaum, Daniel; Estrada, Juan; Gallant, Paul; Germain, Julie; Gu, Yan; Harmange, Jean-Christophe; Kaufman, Stephen A.; Kendall, Rick; Kim, Joseph L.; Kumar, Gondi N.; Long, Alexander M.; Neervannan, Seshadri; Patel, Vinod F.; Polverino, Anthony; Rose, Paul; Van Der Plas, Simon; Whittington, Douglas; Zanon, Roger; Zhao, Huilin
Journal of Medicinal Chemistry, 2007 , vol. 50, # 18 p. 4351 - 4373

619-10-32-氯-5-硝基苯酚

1009-36-52-氯-5-硝基茴香醚

参考文献

CHEMOCENTRYX
Patent: WO2004/46092 A2, 2004 ;
Location in patent: Page 53-55 ;
WO 2004/046092 A2

619-10-32-氯-5-硝基苯酚+

106-94-5溴丙烷

76464-50-14-氯-3-丙氧基硝基苯

参考文献

NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2007/65662 A2, 2007 ;
Location in patent: Page/Page column 48 ;
WO 2007/065662 A2

619-10-32-氯-5-硝基苯酚+

107-08-41-碘丙烷

76464-50-14-氯-3-丙氧基硝基苯

参考文献

Mitsubishi Chemical Industries, Ltd.
Patent: US4292070 A1, 1981 ;

75-30-92-碘代丙烷+

619-10-32-氯-5-硝基苯酚

76464-51-2

参考文献

Baumann, Karlheinz; Flohr, Alexander; Jacobsen, Helmut; Jolidon, Synese; Luebbers, Thomas
Patent: US2008/280948 A1, 2008 ;
Location in patent: Page/Page column 22 ;
US 20080280948 A1

619-10-32-氯-5-硝基苯酚+

100-39-0溴化苄

76464-61-4

参考文献

F2G LIMITED
Patent: US2011/9390 A1, 2011 ;
Location in patent: Page/Page column 16 ;

619-10-32-氯-5-硝基苯酚+

100-44-7苄基氯

76464-61-4

参考文献

JANSSEN PHARMACEUTICA NV
Patent: WO2008/155421 A2, 2008 ;
Location in patent: Page/Page column 62 ;