1-氯-3,5-二硝基苯合成路线 （共 15 条）
反应条件
1: With hydrogenchloride; sodium nitrite in water T=0°C; 0.0833333 h; 2: With copper(l) chloride in water; toluene T=60°C; 1 h; Heating / reflux;
参考文献
Boehringer Ingelheim Pharmaceuticals, Inc.
Patent: US6353013 B1, 2002 ;
Location in patent: Page column 28 ;
反应条件
potassium chloride; tetraphthaloyl chloride in sulfolane T=180°C; 9 h;
参考文献
Lee, Woong Hee; Park, Gyoo Soon; Kim, Seok Chan
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 8 p. 2820 - 2822
反应条件
trichloroisocyanuric acid; sulfuric acid T=130°C; 2 h;
参考文献
Mendona, Gabriela Fonseca; Senra, Monica Rufino; Esteves, Pierre M.; De Mattos, Marcio C.S.
Applied Catalysis A: General, 2011 , vol. 401, # 1-2 p. 176 - 181
反应条件
1: sodium chlorate; nitric acid 2: potassium chloride; tetraphthaloyl chloride / sulfolane / 9 h / 180 °C View Scheme
参考文献
Bulletin of the Korean Chemical Society, , vol. 32, # 8 p. 2820 - 2822
反应条件
in water T=100.1°C; ΔH(excit.), ΔS(excit.); other temp.; Rate constantThermodynamic dataKinetics;
参考文献
Journal of Organic Chemistry, , vol. 50, # 7 p. 1041 - 1045
反应条件
in water T=125.6°C; ΔH(excit.), ΔS(excit.); other temp.; Rate constantThermodynamic dataKinetics;
参考文献
Journal of Organic Chemistry, , vol. 50, # 7 p. 1041 - 1045
反应条件
nitric acid in various solvent(s) Rate constantProduct distribution;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 1457 - 1464
反应条件
hydrogenchloride; sulfuric acid; nitric acid T=130°C; 0.166667 h; Rate constantProduct distribution;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 667 - 674
反应条件
hydrogenchloride; sulfuric acid; nitric acid T=130°C; 0.666667 h; Product distribution;
参考文献
Melhuish, Martin W.; Moodie, Roy B.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 667 - 674
反应条件
1: 57 percent / Na / 70 h / 80 °C 2: 1.) H2/Pt/C; 2.) NaHCO3 / 1.) THF, DMSO, NH3, H2O; 15 deg C; 1.5 h; 2.) H2O, THF; 0 deg C; 30 min 3: 1.)Li2PdCl4, 2.)KOH / 1.)50 deg C, 3 h; 2.)20 deg C, 30 min, methanol View Scheme
参考文献
Martin, Pierre
Helvetica Chimica Acta, 1988 , vol. 71, p. 344 - 347
