吡嗪-2-羧酸甲酯合成路线

参考文献

Goodson, Patricia A.; Oki, Aderemi R.; Glerup, Jorgen; Hodgson, Derek J.
Journal of the American Chemical Society, 1990 , vol. 112, # 17 p. 6248 - 6254

98-97-52-甲酸吡嗪

6164-79-0吡嗪-2-羧酸甲酯

参考文献

ENVIVO PHARMACEUTICALS, INC.; RIPKA, Amy; SHAPIRO, Gideon; MCRINER, Andrew
Patent: WO2012/40230 A1, 2012 ;
Location in patent: Page/Page column 89-90 ;
WO 2012/040230 A1

290-37-9吡嗪+

600-23-7

6164-79-0吡嗪-2-羧酸甲酯

参考文献

Coppa, Fausta; Fontana, Francesca; Lazzarini, Edoardo; Minisci, Francesco; Pianese, Guiseppe; Zhao, Lihua
Tetrahedron Letters, 1992 , vol. 33, # 21 p. 3057 - 3060

98-97-52-甲酸吡嗪+

74-88-4甲基碘

6164-79-0吡嗪-2-羧酸甲酯

参考文献

AstraZeneca AB; NPS PHARMACEUTICALS, INC.
Patent: US2007/259862 A1, 2007 ;
Location in patent: Page/Page column 25-26 ;
US 20070259862 A1

67-56-1甲醇+

1254073-95-4

6164-79-0吡嗪-2-羧酸甲酯

参考文献

WO2010/125102 A1, ;

Page/Page column 125 ;
WO 2010/125102 A1

参考文献

Albaneze-Walker, Jennifer; Bazaral, Charles; Leavey, Tanya; Dormer, Peter G.; Murry, Jerry A.
Organic Letters, 2004 , vol. 6, # 13 p. 2097 - 2100

186581-53-3重氮甲烷+

98-97-52-甲酸吡嗪

6164-79-0吡嗪-2-羧酸甲酯

参考文献

Silva, Nilda M; Tributino, Jorge L.M; Miranda, Ana L.P; Barreiro, Eliezer J; Fraga, Carlos A.M
European Journal of Medicinal Chemistry, 2002 , vol. 37, # 2 p. 163 - 170

98-97-52-甲酸吡嗪+

75-36-5乙酰氯

6164-79-0吡嗪-2-羧酸甲酯

参考文献

US6297235 B1, ;

89-01-0吡嗪-2,3-二羧酸

6164-79-0吡嗪-2-羧酸甲酯

参考文献

Journal of the American Chemical Society, , vol. 62, p. 664

67-56-1甲醇+

19847-10-0吡嗪-2-甲酰氯

6164-79-0吡嗪-2-羧酸甲酯