1: 1-bromo-4-methoxy-benzene With magnesium in tetrahydrofuran 1 h; Inert atmosphereReflux; 2: carbonic acid dimethyl ester in tetrahydrofuran 4 h; Inert atmosphereReflux; 3: With water in tetrahydrofuran T=20°C; Inert atmosphere;
参考文献
Guieu, Samuel; Rocha, Joao; Silva, Artur M.S.
Tetrahedron Letters, 2013 , vol. 54, # 22 p. 2870 - 2873
in diethyl ether byproducts: (CH3OC6F4)2CO, C6F5(2-CH3OC6F5)CO, (C6F5)3COH; addition of the ester (solution in ether) drop by drop to C6F5Li at -78°C, 0.5 hours, warming to 20°C and hydrolysis;;
