甲基3-羟基-3-甲基丁酸酯合成路线 （共 12 条）
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Gey et al.
Helvetica Chimica Acta, 1957 , vol. 40, p. 2354,2365
Full Text Show Details
Searles et al.
Journal of Organic Chemistry, 1959 , vol. 24, p. 1770,1773
反应条件
T=335.1 - 390.4°C; pyrolysis; Ea; k(600 K); KineticsThermodynamic data;
参考文献
Zapata, Edilma; Gaviria, Jair; Quijano, Jairo
International Journal of Chemical Kinetics, 2007 , vol. 39, # 2 p. 92 - 96
反应条件
1: methyl acetate With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane
T=-78°C; 1.5 h;
2: acetone in tetrahydrofuran; hexane
T=20°C;
参考文献
Citron, Christian A.; Rabe, Patrick; Dickschat, Jeroen S.
Journal of Natural Products, 2012 , vol. 75, # 10 p. 1765 - 1776
参考文献
MITSUBISHI RAYON CO., LTD
Patent: EP467721 A1, 1992 ;
反应条件
caesium carbonate in N,N-dimethyl-formamide
T=20°C;
参考文献
MERCK and CO., INC.
Patent: WO2007/108968 A2, 2007 ;
Location in patent: Page/Page column 40 ;
参考文献
Searles et al.
Journal of Organic Chemistry, 1959 , vol. 24, p. 1770,1773
反应条件
T=25°C; Irradiation; Further byproducts given;
参考文献
Tomioka, Hideo; Okuno, Hiroshi; Izawa, Yasuji
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1636 - 1641
反应条件
benzophenone
T=25°C; Irradiation; Further byproducts given;
参考文献
Tomioka, Hideo; Okuno, Hiroshi; Izawa, Yasuji
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1636 - 1641
参考文献
Ruzicka et al.
Helvetica Chimica Acta, 1941 , vol. 24, p. 1455
反应条件
nitric acid; iron nitrate (III)
参考文献
Schaafsma,S.E. et al.
Recueil des Travaux Chimiques des Pays-Bas, 1968 , vol. 87, p. 1301 - 1312
