丙二酸单乙酯钾盐合成路线

参考文献

Sun, Chong-Qing; Cheng, Peter T.W.; Stevenson, Jay; Dejneka, Tamara; Brown, Baerbel; Wang, Tammy C.; Robl, Jeffrey A.; Poss, Michael A.
Tetrahedron Letters, 2002 , vol. 43, # 7 p. 1161 - 1164

6148-64-7丙二酸单乙酯钾盐+

4659-45-42,6-二氯苯甲酰氯

72835-87-13-(2,6-二氯苯基)-3-氧代丙酸乙酯

参考文献

Hanan, Emily J.; Van Abbema, Anne; Barrett, Kathy; Blair, Wade S.; Blaney, Jeff; Chang, Christine; Eigenbrot, Charles; Flynn, Sean; Gibbons, Paul; Hurley, Christopher A.; Kenny, Jane R.; Kulagowski, Janusz; Lee, Leslie; Magnuson, Steven R.; Morris, Claire; Murray, Jeremy; Pastor, Richard M.; Rawson, Tom; Siu, Michael; Ultsch, Mark; Zhou, Aihe; Sampath, Deepak; Lyssikatos, Joseph P.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 22 p. 10090 - 10107

51-44-53,4-二氯苯甲酸+

6148-64-7丙二酸单乙酯钾盐

53090-43-03-(3,4-二氯苯基)-3-氧代丙酸乙酯

参考文献

BIOENERGENIX; MCCALL, John; KELLY, Robert, C.; ROMERO, Donna, L.
Patent: WO2014/66795 A1, 2014 ;
Location in patent: Paragraph 0175 ;

6148-64-7丙二酸单乙酯钾盐+

3024-72-43,4-二氯苯甲酰氯

53090-43-03-(3,4-二氯苯基)-3-氧代丙酸乙酯

参考文献

Takamura, Makoto; Yabu, Kazuo; Nishi, Takahide; Yanagisawa, Hiroaki; Kanai, Motomu; Shibasaki, Masakatsu
Synlett, 2003 , # 3 p. 353 - 356

50-75-92,3,4-三氯苯甲酸+

6148-64-7丙二酸单乙酯钾盐

63131-34-03-氧代-3-(2,3,4-三氯苯基)丙酸乙酯

参考文献

DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1336611 A1, 2003 ;

402-43-7对溴三氟甲苯+

6148-64-7丙二酸单乙酯钾盐

721-63-14-(三氟甲基)苯乙酸乙酯

参考文献

Tetrahedron, , vol. 68, # 9 p. 2113 - 2120

6148-64-7丙二酸单乙酯钾盐+

98-56-6对氯三氟甲苯

721-63-14-(三氟甲基)苯乙酸乙酯

参考文献

Tetrahedron, , vol. 68, # 9 p. 2113 - 2120

5292-21-7环己基乙酸+

6148-64-7丙二酸单乙酯钾盐

64127-44-24-环己基-3-氧代丁酸乙酯

参考文献

Boyd, Steven A.; Mantei, Robert A.; Tasker, Andrew S.; Liu, Gang; Sorensen, Bryan K.; Henry Jr., Kenneth J.; Von Geldern, Thomas W.; Winn, Martin; Wu-Wong, Jinshyun R.; Chiou, William J.; Dixon, Douglas B.; Hutchins, Charles W.; Marsh, Kennan C.; Nguyen, Bach; Opgenorth, Terry J.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 6 p. 991 - 1002

59-67-6烟酸+

6148-64-7丙二酸单乙酯钾盐

6283-81-43-氧代-3-(3-吡啶基)丙酸乙酯

参考文献

Bayer Healthcare AG
Patent: WO2004/29055 A1, 2004 ;
Location in patent: Page 52-53 ;
WO 2004/029055 A1

10400-19-8吡啶-3-羧酸酰氯+

6148-64-7丙二酸单乙酯钾盐

6283-81-43-氧代-3-(3-吡啶基)丙酸乙酯

参考文献

GLAXO GROUP LIMITED; JOHNS, Brian Alvin; SHOTWELL, John Brad
Patent: WO2012/67664 A1, 2012 ;
Location in patent: Page/Page column 28-29 ;