1: 2-nitromalonaldehyde; 4-methoxy-aniline With hydrogenchloride in water 0.166667 h; 2: p-methoxyphenylammonium chloride With acetic acid in water 0.333333 h; Inert atmosphereReflux; 3: With thiophenol in water 50 h; RefluxInert atmosphere;
参考文献
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE; PINKERTON, Anthony, B.; DAHL, Russell; COSFORD, Nicholas, D.P.; MILLAN, Jose, Luis
Patent: WO2013/126608 A1, 2013 ;
Location in patent: Paragraph 00670 ;