1-(4-羧基苯基)-3-甲基-5-吡唑酮合成路线 （共 6 条）
反应条件
in ethanol 2.5 h; Reflux;
参考文献
Bianchini, Roberto; Bonanni, Marco; Corsi, Massimo; Infantino, Angela Simona
Tetrahedron, 2012 , vol. 68, # 41 p. 8636 - 8644
反应条件
1.1: hydrogenchloride; sodium nitrite / -10 - -5 °C 1.2: -10 - -5 °C 2.1: acetic acid / 12 h / Reflux View Scheme
参考文献
Chemistry and Biology, , vol. 17, # 5 p. 471 - 482
反应条件
1: With chloroformic acid ethyl ester; triethylamine in chloroform T=0 - 21°C; 2.33333 h; 2: With sodium tetrahydroborate; water T=20 - 35°C; 2.1 h; 3: With hydrogenchloride in water pH=4;
参考文献
Nidek Co., Ltd.
Patent: EP1666537 A1, 2006 ;
Location in patent: Page/Page column 7 ;
反应条件
sodium tetrahydroborate; triethylamine in tetrahydrofuran; chloroform; water
参考文献
Mitsubishi Chemical Industries Limited
Patent: US4857542 A1, 1989 ;
