1: 1-amino-2,3-dichlorobenzene With sulfuric acid; sodium nitrite in water T=0 - 5°C; 1 h; 2: With sodium hydroxide in water T=0 - 5°C; 3: copper (I) cyanide With sodium cyanide in water T=65 - 70°C; 0.5 h;
参考文献
RPG Life Sciences Limited
Patent: US6639072 B1, 2003 ;
Location in patent: Page/Page column 7 ;
Bennett, Lawrence R.; Blankley, C. John; Fleming, Robert W.; Smith, Ronald D.; Tessman, Deirdre K.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 4 p. 382 - 389
