3-(4-碘苯基)-1-丙醇合成路线 （共 8 条）
反应条件
pyridinium chlorochromate in dichloromethane 1 h;
参考文献
Nogradi, Mihaly; Keserue, Gyoergy M.; Kajtar-Peredy, Maria; Vermes, Borbala; Ha, Nguyen Thi Thu; Dinya, Zoltan
ACH - Models in Chemistry, 1998 , vol. 135, # 1-2 p. 57 - 78
反应条件
borane-THF in tetrahydrofuran
T=20°C; 6 h;
参考文献
RIB-X-PHARMACEUTICALS, INC.
Patent: WO2008/106204 A1, 2008 ;
Location in patent: Page/Page column 116 ;
反应条件
diisobutylaluminium hydride in hexane; toluene
T=-60 - -10°C; 2 h; Inert atmosphere;
参考文献
Cheung, Siu-Yin; Chow, Hak-Fun; Ngai, To; Wei, Xiaoling
Chemistry - A European Journal, 2009 , vol. 15, # 10 p. 2278 - 2288
反应条件
(i) aq. NaIO4, I2, AcOH, H2SO4, (ii) KOH, MeOH; Multistep reaction;
参考文献
Newton,B.N.
Journal of Medicinal Chemistry, 1976 , vol. 19, p. 1362 - 1366
参考文献
Lafayette Pharmacal, Inc.
Patent: US4022814 A1, 1977 ;
反应条件
1: sodium hydride / tetrahydrofuran
2: sodium chloride / dimethyl sulfoxide
3: diisobutylaluminium hydride
View Scheme
参考文献
Jayasekara, P. Suresh; Barrett, Matthew O.; Ball, Christopher B.; Brown, Kyle A.; Hammes, Eva; Balasubramanian, Ramachandran; Harden, T. Kendall; Jacobson, Kenneth A.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 9 p. 3874 - 3883
反应条件
diisobutylaluminium hydride
参考文献
Jayasekara, P. Suresh; Barrett, Matthew O.; Ball, Christopher B.; Brown, Kyle A.; Hammes, Eva; Balasubramanian, Ramachandran; Harden, T. Kendall; Jacobson, Kenneth A.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 9 p. 3874 - 3883
反应条件
pyridine in chloroform
参考文献
Newton,B.N.
Journal of Medicinal Chemistry, 1976 , vol. 19, p. 1362 - 1366
