2,4,6-三甲基苯硼酸合成路线 （共 68 条）
反应条件
palladium diacetate; sodium carbonate; triphenylphosphine in ethylene glycol dimethyl ether; water; isopropyl alcohol
Heating;
参考文献
Zhang, Zhaoda; Greenfield, Matthew T.; Spiller, Marga; McMurry, Thomas J.; Lauffer, Randall B.; Caravan, Peter
Angewandte Chemie - International Edition, 2005 , vol. 44, # 41 p. 6766 - 6769
反应条件
[Fe(phthalocyanine)]; palladium diacetate; (S)-4-Isopropyl-2-[2-(toluene-4-sulfinyl)-phenyl]-4,5-dihydro-oxazole in dimethyl sulfoxide
T=80°C; 12 h; regioselective reaction;
参考文献
Yamaguchi, Kazuya; Kondo, Hiroki; Yamaguchi, Junichiro; Itami, Kenichiro
Chemical Science, 2013 , vol. 4, # 9 p. 3753 - 3757
反应条件
potassium tert-butylate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether; tert-butyl alcohol
T=50 - 90°C; Suzuki Coupling; 0.75 h;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2005/99688 A2, 2005 ;
Location in patent: Page/Page column 197 ;
WO 2005/099688 A2
反应条件
1: With dichloro bis(acetonitrile) palladium(II); sodium carbonate in water
T=45°C; 8 h;
2: Suzuki-Miyaura Coupling;
参考文献
Ganesamoorthy; Shanmugasundaram; Karvembu
Journal of Molecular Catalysis A: Chemical, 2013 , vol. 371, p. 118 - 124
反应条件
potassium fluoride; tris(dibenzylideneacetone)dipalladium (0); tri-tert-butyl phosphine in tetrahydrofuran
T=20°C; Suzuki cross-coupling; 16 h;
参考文献
Littke, Adam F.; Dai, Chaoyang; Fu, Gregory C.
Journal of the American Chemical Society, 2000 , vol. 122, # 17 p. 4020 - 4028
反应条件
potassium phosphate; tris(dibenzylideneacetone)dipalladium (0); tri-cyclo-hexyl-phosphine in toluene
T=90°C; Suzuki cross-coupling; 37 h; Title compound not separated from byproducts.;
参考文献
Littke, Adam F.; Dai, Chaoyang; Fu, Gregory C.
Journal of the American Chemical Society, 2000 , vol. 122, # 17 p. 4020 - 4028
反应条件
palladium diacetate; triphenylphosphine; cesium fluoride in ethylene glycol dimethyl ether
T=70°C; Suzuki coupling; 6 h;
参考文献
Castanet, Anne-Sophie; Colobert, Francoise; Broutin, Pierre-Emmanuel; Obringer, Michel
Tetrahedron Asymmetry, 2002 , vol. 13, # 6 p. 659 - 665
反应条件
C16H36N(1+)*C32H25Cl2Fe2N2O3PdS(1-); potassium carbonate in water
Suzuki coupling; 0.25 h; Microwave irradiation;
参考文献
Hanhan, Murat Emre; Martinez-Manez, Ramon; Ros-Lis, Jose Vicente
Tetrahedron Letters, 2012 , vol. 53, # 19 p. 2388 - 2391
反应条件
cis,cis,cis-tetrakis[(diphenylphosphanyl)methyl]cyclopentane; potassium carbonate; bis(η3-allyl-μ-chloropalladium(II)) in xylene
T=130°C; Suzuki cross-coupling; 20 h;
参考文献
Chahen, Ludovic; Doucet, Henri; Santelli, Maurice
Synlett, 2003 , # 11 p. 1668 - 1672
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethylene glycol dimethyl ether; water
T=100°C; Suzuki-Miyaura cross-coupling; 4 h; Inert atmosphereLarge scale reaction;
参考文献
Henry, Nicolas; Enguehard-Gueiffier, Cecile; Thery, Isabelle; Gueiffier, Alain
European Journal of Organic Chemistry, 2008 , # 28 p. 4824 - 4827
