1-氯-4-(4-氯苯基)-2-丁醇合成路线 （共 2 条）
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in water; toluene T=0 - 95°C; 3 h;
参考文献
RICHTER GEDEON VEGYESZETI GYAR RT.
Patent: WO2005/70897 A1, 2005 ;
Location in patent: Page/Page column 7 ;
反应条件
1: 4-chloro-benzyl chloride With iodine; magnesium in diethyl ether
0.25 h; Heating;
2: epichlorohydrin in diethyl ether
2 h; Heating; Further stages.;
参考文献
Roman, Gheorghe; Riley, John G.; Vlahakis, Jason Z.; Kinobe, Robert T.; Brien, James F.; Nakatsu, Kanji; Szarek, Walter A.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 9 p. 3225 - 3234
