异噻唑烷 1,1-二氧化物合成路线 （共 10 条）
反应条件
sodium ethanolate in ethanol T=20°C; 5 h; Heating / reflux;
参考文献
GLAXO GROUP LIMITED
Patent: WO2004/50619 A1, 2004 ;
Location in patent: Page 24 ;
WO 2004/050619 A1
反应条件
n-butyllithium; 1,10-phenanthroline; diisopropylamine in tetrahydrofuran; hexane T=-60 - 0°C; 2 h;
参考文献
Lee, Jaemoon; Zhong, Yong-Li; Reamer, Robert A.; Askin, David
Organic Letters, 2003 , vol. 5, # 22 p. 4175 - 4177
反应条件
n-butyllithium; 1,10-phenanthroline; diisopropylamine in tetrahydrofuran; hexane T=-50 - 0°C; 4 h;
参考文献
Organic Letters, , vol. 5, # 22 p. 4175 - 4177
反应条件
chloroform; sulfur dioxide; chlorine teilweise unter Bestrahlung mit UV-Licht und Behandlung des Reaktionsprodukts mit wss. NaOH;
参考文献
Chemische Berichte, , vol. 96, p. 3068 - 3075
DE932676 , ;
GB752227 , ;
US2866786 , ;
GB786059 , ;
反应条件
sodium periodate; borate buffer 3 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 55, # 9 p. 2580 - 2586
反应条件
sodium carbonate in chloroform Heatingother sultams, var. reagents; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 52, # 11 p. 2162 - 2166
反应条件
copper(l) iodide; potassium carbonate; o-dppdH in N,N-dimethyl-formamide
T=110°C; 40 h; Inert atmosphere;
参考文献
Han, Xiaojun
Tetrahedron Letters, 2010 , vol. 51, # 2 p. 360 - 362
反应条件
copper(I) oxide; caesium carbonate in water
T=130°C; 24 h; Sealed tube;
参考文献
Tan, Bryan Yong-Hao; Teo, Yong-Chua; Seow, Ai-Hua
European Journal of Organic Chemistry, 2014 , vol. 2014, # 7 p. 1541 - 1546
反应条件
in methanol; hexane; water; ethyl acetate
参考文献
Pfizer Inc.
Patent: US4489075 A1, 1984 ;
反应条件
1: With 1H-indene-1,3(2H)-dione; [Cu(I)(CH3CN)4]PF6
T=23°C; 0.25 h;
2: With 3-CF3C6H4O3t-Bu
T=23°C; 72 h; Inert atmosphere;
参考文献
Powell, David A.; Fan, Hope
Journal of Organic Chemistry, 2010 , vol. 75, # 8 p. 2726 - 2729
