Alpha-甲酰基苯乙酸甲酯合成路线 （共 17 条）
反应条件
1: aluminium amalgam; water 2: aq. barium hydroxide solution View Scheme
参考文献
Wislicenus; Bilhuber
Chemische Berichte, 1918 , vol. 51, p. 1237
反应条件
hydrogenchloride; sodium borohydride; tetrabutyl-ammonium chloride; sodium carbonate in tert-butyl methyl ether; water
参考文献
Ganes Chemicals Inc.
Patent: US5250744 A1, 1993 ;
反应条件
trimethylsilyl trifluoromethanesulfonate; boron trifluoride diethyl etherate
T=0°C; Ring cleavage; rearrangement; addition; 0.0833333 h;
参考文献
Garcia Ruano, Jose L.; Garcia Paredes, Cristina
Tetrahedron Letters, 2000 , vol. 41, # 28 p. 5357 - 5361
反应条件
titanium tetrachloride; triethylamine in dichloromethane
T=0 - 23°C; 2 h; Inert atmosphere;
参考文献
Jolit, Anais; Vazquez-Rodriguez, Saleta; Yap, Glenn P. A.; Tius, Marcus A.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 42 p. 11102 - 11105
Angewandte Chemie, 2013 , vol. 125, # 42 p. 11308 - 11311,4
反应条件
1: dichloromethane / 20 °C
2: triethylamine / dichloromethane / 2 h / 20 °C
3: CuSO4‵5H2O / tetrahydrofuran; water
View Scheme
参考文献
Kowalkowska, Anna; Jonczyk, Andrzej
Synthetic Communications, 2011 , vol. 41, # 22 p. 3308 - 3317
反应条件
1: triethylamine / dichloromethane / 2 h / 20 °C
2: CuSO4‵5H2O / tetrahydrofuran; water
View Scheme
参考文献
Kowalkowska, Anna; Jonczyk, Andrzej
Synthetic Communications, 2011 , vol. 41, # 22 p. 3308 - 3317
反应条件
1: dichloromethane / Cooling
2: triethylamine / dichloromethane / 2 h / 20 °C
3: CuSO4‵5H2O / tetrahydrofuran; water
View Scheme
参考文献
Kowalkowska, Anna; Jonczyk, Andrzej
Synthetic Communications, 2011 , vol. 41, # 22 p. 3308 - 3317
反应条件
2: triethylamine / dichloromethane / 2 h / 20 °C
3: CuSO4‵5H2O / tetrahydrofuran; water
View Scheme
参考文献
Kowalkowska, Anna; Jonczyk, Andrzej
Synthetic Communications, 2011 , vol. 41, # 22 p. 3308 - 3317
反应条件
1: tetrabutylammomium bromide; potassium carbonate / acetonitrile / 10.17 h / 65 - 70 °C
2: dichloromethane / Cooling
3: triethylamine / dichloromethane / 2 h / 20 °C
4: CuSO4‵5H2O / tetrahydrofuran; water
View Scheme
参考文献
Kowalkowska, Anna; Jonczyk, Andrzej
Synthetic Communications, 2011 , vol. 41, # 22 p. 3308 - 3317
反应条件
1: triethylamine / dichloromethane / 2 h / 20 °C
2: CuSO4‵5H2O / tetrahydrofuran; water
View Scheme
参考文献
Kowalkowska, Anna; Jonczyk, Andrzej
Synthetic Communications, 2011 , vol. 41, # 22 p. 3308 - 3317
