3,3-二甲基-1-(1H-1,2,4-三唑-1-基)丁-2-酮合成路线 （共 15 条）
反应条件
hydrogenchloride; sodium nitrite T=0 - 20°C;
参考文献
Astleford, Bret A.; Goe, Gerald L.; Keay, James G.; Scriven, Eric F. V.
Journal of Organic Chemistry, 1989 , vol. 54, # 3 p. 731 - 732
反应条件
potassium carbonate in di-isopropyl ether; acetone
反应条件
sodium hydride in tetrahydrofuran 0.5 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 8 p. 1497 - 1502
反应条件
in tetrahydrofuran T=60°C; 12 h;
参考文献
Rentzea, Costin N.
Angewandte Chemie, 1986 , vol. 98, # 7 p. 644 - 645
反应条件
1: Br2 / CHCl3 / 0.25 h / Ambient temperature 2: NaH / tetrahydrofuran / 0.5 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 8 p. 1497 - 1502
反应条件
1: acetonitrile / 80 - 85 °C 2: conc. H2SO4, NaNO2 / H2O / 2 h / 0 - 20 °C View Scheme
参考文献
Doklady Chemistry, , vol. 308, # 4-6 p. 299 - 301
Dokl. Akad. Nauk SSSR Ser. Khim., , vol. 308, # 5 p. 1155 - 1158
反应条件
in acetone T=25 - 30°C; Decomposition; 4 h; UV-irradiation; Further byproducts given;
参考文献
Pesticide Science, , vol. 48, # 3 p. 247 - 252
反应条件
1: in water 4 h; Heating; 2: With acetic anhydride T=106 - 109°C; 3 h;
参考文献
Wang, Shuowen; Shi, Bojie; Li, Yuchang; Wang, Qingmin; Huang, Runqiu
Synthetic Communications, 2003 , vol. 33, # 9 p. 1449 - 1457
反应条件
acetic anhydride T=40°C; 0.25 h; Yield given;
参考文献
Ogata, Masaru; Matsumoto, Hiroshi; Kida, Shiro; Shimizu, Sumio; Tawara, Katsuya; Kawamura, Yoshimi
Journal of Medicinal Chemistry, 1987 , vol. 30, # 8 p. 1497 - 1502
反应条件
1: morpholine, AcOH / benzene 2: NaBH4 / methanol View Scheme
参考文献
Min, Yong Ki; Asami, Tadao; Fujioka, Shozo; Murofushi, Noboru; Yamaguchi, Isomaro; Yoshida, Shigeo
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 3 p. 425 - 430
