4-氨基-1-哌啶甲酸乙酯合成路线

20662-53-74-（2-酮酸-1-苯并咪唑）哌啶

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 6 p. 1687 - 1691

185961-99-31,3-二氢-1-(4-哌啶基)-2H-咪唑并[4,5-b]吡啶-2-酮

参考文献

Burgey, Christopher S.; Stump, Craig A.; Nguyen, Diem N.; Deng, James Z.; Quigley, Amy G.; Norton, Beth R.; Bell, Ian M.; Mosser, Scott D.; Salvatore, Christopher A.; Rutledge, Ruth Z.; Kane, Stefanie A.; Koblan, Kenneth S.; Vacca, Joseph P.; Graham, Samuel L.; Williams, Theresa M.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 19 p. 5052 - 5056

463-71-8硫光气+

58859-46-44-氨基-1-哌啶甲酸乙酯

73733-70-74-异硫氰酸基哌啶-1-羧酸乙酯

参考文献

PFIZER INC.
Patent: WO2004/74283 A1, 2004 ;
Location in patent: Page 33; 34; 219 ;
WO 2004/074283 A1

541-41-3氯甲酸乙酯+

58859-46-44-氨基-1-哌啶甲酸乙酯

73733-70-74-异硫氰酸基哌啶-1-羧酸乙酯

参考文献

Janssen Pharmaceutica N.V.
Patent: US4943580 A1, 1990 ;

75-15-0二硫化碳+

58859-46-44-氨基-1-哌啶甲酸乙酯

73733-70-74-异硫氰酸基哌啶-1-羧酸乙酯

参考文献

Roman, Gheorghe; Crandall, Ian E.; Szarek, Walter A.
ChemMedChem, 2013 , vol. 8, # 11 p. 1795 - 1804

4857-06-12-氯苯并咪唑+

58859-46-44-氨基-1-哌啶甲酸乙酯

73734-07-34-(1H-苯并咪唑-2-基氨基)-1-哌啶羧酸乙酯

参考文献

Ishikawa, Minoru; Kubota, Dai; Yamamoto, Mikio; Kuroda, Chizuko; Iguchi, Maki; Koyanagi, Akihiro; Murakami, Shoichi; Ajito, Keiichi
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 7 p. 2109 - 2130

58859-46-44-氨基-1-哌啶甲酸乙酯

73734-07-34-(1H-苯并咪唑-2-基氨基)-1-哌啶羧酸乙酯

参考文献

Roman, Gheorghe; Crandall, Ian E.; Szarek, Walter A.
ChemMedChem, 2013 , vol. 8, # 11 p. 1795 - 1804

4857-06-12-氯苯并咪唑+

58859-46-44-氨基-1-哌啶甲酸乙酯+

497-19-8碳酸钠

73734-07-34-(1H-苯并咪唑-2-基氨基)-1-哌啶羧酸乙酯

参考文献

Meiji Seika Kaisha, Ltd.
Patent: US6420558 B1, 2002 ;

58859-46-44-氨基-1-哌啶甲酸乙酯+

208398-29-2

73734-07-34-(1H-苯并咪唑-2-基氨基)-1-哌啶羧酸乙酯

参考文献

Hong, Yaping; Senanayake, Chris H.; Xiang, Tingjian; Vandenbossche, Charles P.; Tanoury, Gerald J.; Bakale, Roger P.; Wald, Stephen A.
Tetrahedron Letters, 1998 , vol. 39, # 20 p. 3121 - 3124

58859-46-44-氨基-1-哌啶甲酸乙酯

75970-47-7(1H-苯并咪唑-2-基)-哌啶-4-胺双氢溴酸

参考文献

Roman, Gheorghe; Crandall, Ian E.; Szarek, Walter A.
ChemMedChem, 2013 , vol. 8, # 11 p. 1795 - 1804