1: NaH / tetrahydrofuran; dimethylformamide / 1.) r.t., 25 min, 2.) r.t., overnight
2: 5percent aq. HCl / ethyl acetate / 5 h / 50 °C
View Scheme
参考文献
Brown, David S.; Elliott, Mark C.; Moody, Christopher J.; Mowlem, Timothy J.; Marino, Joseph P.; Padwa, Albert
Journal of Organic Chemistry, 1994 , vol. 59, # 9 p. 2447 - 2455
sodium tetrahydroborate; 18-crown-6 ether; potassium tert-butylate in dimethyl sulfoxide
T=20°C; 2 h; Yield given. Further byproducts given. Yields of byproduct given;
参考文献
Grigoryan, G. S.; Tovmasyan, V. S.; Malkhasyan, A. Ts.; Martirosyan, G. T.; Beletskaya, I. P.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 1.1 p. 50 - 56
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 1 p. 61 - 68