2-(甲氧基甲氧基)苯甲酸合成路线 （共 7 条）
反应条件
piperazine in N,N-dimethyl acetamide T=150°C; Substitution; 0.5 h;
参考文献
Nishioka, Hiroyasu; Nagasawa, Masaaki; Yoshida, Kiyoshi
Synthesis, 2000 , # 2 p. 243 - 246
反应条件
lithium hydroxide in methanol; water
4 h; Heating;
参考文献
Regents of the University of Minnesota
Patent: US2008/293666 A1, 2008 ;
Location in patent: Page/Page column 55 ;
反应条件
1: NaH / benzene
2: aq. KOH
View Scheme
参考文献
Dunn,B.M.; Bruice,T.C.
Journal of the American Chemical Society, 1971 , vol. 93, p. 5725 - 5731
反应条件
ethanol
durch Behandeln mit alkoh. Kalilauge;
参考文献
Reychler
Bulletin de la Societe Chimique de France, 1907 , vol. <4> 1, p. 1196
Chem. Zentralbl., 1908 , vol. 79, # I p. 716
反应条件
n-butyllithium
1.) ether, hexane, 2 h, r.t., 2.) 5 min, r.t.; Yield given. Multistep reaction;
参考文献
Townsend, Craig A.; Bloom, Leslie M.
Tetrahedron Letters, 1981 , vol. 22, # 40 p. 3923 - 3924
反应条件
dicyclohexyl-carbodiimide in tetrahydrofuran
T=0 - 20°C; 2.5 h;
参考文献
Regents of the University of Minnesota
Patent: US2008/293666 A1, 2008 ;
Location in patent: Page/Page column 55 ;
反应条件
1: 1.) diethyl phosphorocyanidate (DEPC), Et3N, 2.) Et3N / 1.) DMF, -15 deg C, 2.) DMF, a) -15 deg C, 2 h, b) RT
2: HCl / methanol / 5 h / Heating
View Scheme
参考文献
Hamada, Yasumasa; Morita, Seiji; Shioiri, Takayuki
Heterocycles, 1982 , vol. 17, p. 321 - 324
