4-丙基-4'-氰基联苯合成路线 （共 11 条）
反应条件
(Ph3P)2Pd(Ph)(I) in N,N-dimethyl-formamide 2 h; Heating;
参考文献
Bumagin, N. A.; Luzikova, E. V.; Beletskaya, I. P.
Russian Journal of Organic Chemistry, 1995 , vol. 31, # 11 p. 1480 - 1486
Zhurnal Organicheskoi Khimii, 1995 , vol. 31, # 11 p. 1650 - 1656
反应条件
acetic anhydride 2 h; Heating;
参考文献
Ruolene, Yu. I.; Adomenas, P. V.; Sirutkaitis, R. A.; Denis, G. I.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, p. 1187 - 1191
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 6 p. 1305 - 1310
反应条件
1: AlCl3 / CH2Cl2 / 5 h / Ambient temperature 2: 1) hydrazine hydrate, 2) KOH / 1) diethylene glycol, 130 deg C, 1 h, 2) diethylene glycol, 130 deg C, 2 h, then 160 deg C, 3 h 3: 1) TiCl4, 2) hydroxylamine hydrochloride, pyridine / 1) CH2Cl2, 0 deg C, 30 min, 2) ethanol, reflux, 2 h 4: 71 percent / acetic anhydride / 2 h / Heating View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 20, p. 1187 - 1191
Zhurnal Organicheskoi Khimii, , vol. 20, # 6 p. 1305 - 1310
反应条件
1: PdCl2(dppf) / tetrahydrofuran; diethyl ether / 20 °C 2: 86 percent / PhPdI(PPh3)2 / dimethylformamide / 2 h / Heating View Scheme
参考文献
Russian Journal of Organic Chemistry, , vol. 31, # 11 p. 1480 - 1486
Zhurnal Organicheskoi Khimii, , vol. 31, # 11 p. 1650 - 1656
反应条件
1: PdCl2(dppf) / tetrahydrofuran; diethyl ether / 20 °C 2: 86 percent / PhPdI(PPh3)2 / dimethylformamide / 2 h / Heating View Scheme
参考文献
Russian Journal of Organic Chemistry, , vol. 31, # 11 p. 1480 - 1486
Zhurnal Organicheskoi Khimii, , vol. 31, # 11 p. 1650 - 1656
反应条件
1: 1) hydrazine hydrate, 2) KOH / 1) diethylene glycol, 130 deg C, 1 h, 2) diethylene glycol, 130 deg C, 2 h, then 160 deg C, 3 h 2: 1) TiCl4, 2) hydroxylamine hydrochloride, pyridine / 1) CH2Cl2, 0 deg C, 30 min, 2) ethanol, reflux, 2 h 3: 71 percent / acetic anhydride / 2 h / Heating View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 20, p. 1187 - 1191
Zhurnal Organicheskoi Khimii, , vol. 20, # 6 p. 1305 - 1310
反应条件
1: 1) TiCl4, 2) hydroxylamine hydrochloride, pyridine / 1) CH2Cl2, 0 deg C, 30 min, 2) ethanol, reflux, 2 h 2: 71 percent / acetic anhydride / 2 h / Heating View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 20, p. 1187 - 1191
Zhurnal Organicheskoi Khimii, , vol. 20, # 6 p. 1305 - 1310
反应条件
1: LiAlH4, AlCl3 2: 1-methyl-pyrrolidin-2-one View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 97 - 102
反应条件
1-methyl-pyrrolidin-2-one
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 97 - 102
反应条件
potassium hydroxide in diethylene glycol T=100°C; Saponification; 12 h;
参考文献
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, , vol. 55, # 7 p. 567 - 575
