反应条件
1: 97 percent / imidazole / dimethylformamide / 18 h / Ambient temperature 2: 1.) LDA / 1.) THF, hexane, -20 deg C, 45 min, 2.) THF, hexane, from -20 deg C to RT, 2.5 h 3: 44 percent / NH4OAc, Cu(OAc)2*H2O, CH3CO2H / 0.67 h / 98 °C 4: 78 percent / aq. K2S2O8, CH3CO2H / 18 h View Scheme
参考文献
Gallagher, Timothy F.; Seibel, George L.; Kassis, Shouki; Laydon, Jeffrey T.; Blumenthal, Mary Jane; Lee, John C.; Lee, Dennis; Boehm, Jeffrey C.; Fier-Thompson, Susan M.; Abt, Jeffrey W.; Soreson, Margaret E.; Smietana, Juanita M.; Hall, Ralph F.; Garigipati, Ravi S.; Bender, Paul E.; Erhard, Karl F.; Krog, Arnold J.; Hofmann, Glenn A.; Sheldrake, Peter L.; McDonnell, Peter C.; Kumar, Sanjay; Young, Peter R.; Adams, Jerry L.
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 1 p. 49 - 64
