4-(2-吡啶甲基)苯胺合成路线 （共 15 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol; ethyl acetate T=20°C;
参考文献
Seto, Masaki; Aramaki, Yoshio; Imoto, Hiroshi; Aikawa, Katsuji; Oda, Tsuneo; Kanzaki, Naoyuki; Iizawa, Yuji; Baba, Masanori; Shiraishi, Mitsuru
Chemical and Pharmaceutical Bulletin, 2004 , vol. 52, # 7 p. 818 - 829
反应条件
1: 57 percent / nitric acid; sulfuric acid / 0.08 h / 50 °C 2: 85 percent / H2 / Pd/C / ethanol; ethyl acetate / 20 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 52, # 7 p. 818 - 829
反应条件
Dimethylammonium sulphite T=150°C; 25 h;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 24, p. 707 - 710
反应条件
Dimethylammonium sulphite T=150°C; 25 h;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 24, p. 707 - 710
反应条件
acetic acid; zinc 1 h; Heating;
参考文献
Katsura; Inoue; Tomoi; Takasugi
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 8 p. 2062 - 2074
反应条件
1: 1.) n-BuLi / 1.) THF, hexane, -60 deg C, 1 h, 2.) THF, hexane, -60 deg C, 2 h 2: 96 percent / SOCl2 / CHCl3 / 1 h / Heating 3: 42 percent / Zn, AcOH / 1 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 40, # 8 p. 2062 - 2074
反应条件
1: 96 percent / SOCl2 / CHCl3 / 1 h / Heating 2: 42 percent / Zn, AcOH / 1 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 40, # 8 p. 2062 - 2074
反应条件
1: 1.) n-BuLi / 1.) THF, hexane, -60 deg C, 1 h, 2.) THF, hexane, -60 deg C, 2 h 2: 96 percent / SOCl2 / CHCl3 / 1 h / Heating 3: 42 percent / Zn, AcOH / 1 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 40, # 8 p. 2062 - 2074
反应条件
1: 70 percent / 24 h / Ambient temperature 2: 25 percent / aq. methylammonium sulphite / 25 h / 150 °C View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 24, p. 707 - 710
反应条件
1: 68 percent / 24 h / Ambient temperature 2: 10 percent / aq. methylammonium sulphite / 25 h / 150 °C View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 24, p. 707 - 710
