2,3,4,6-四溴间甲酚合成路线 （共 12 条）
反应条件
1: 83 percent / aluminium chloride / benzene / 0.5 h / Heating 2: 34 percent / nitric acid, acetic acid / 4 h / 15 - 16 °C / further nitration agents 3: 97 percent / potassium carbonate / dimethylformamide / 14 h / Ambient temperature 4: 8 percent / potassium carbonate, copper(II) oxide / 16 h / 140 °C View Scheme
参考文献
Carvalho, Christopher F.; Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1613 - 1620
反应条件
1: 83 percent / aluminium chloride / benzene / 0.5 h / Heating 2: 18 percent / nitric acid, acetic acid / 4 h / 15 - 16 °C / further nitration agents 3: potassium carbonate / dimethylformamide / 14 h / Ambient temperature 4: 17 percent / potassium carbonate, copper(II) oxide / 16 h / 140 °C View Scheme
参考文献
Carvalho, Christopher F.; Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1613 - 1620
参考文献
Baeyer; Seuffert
Chemische Berichte, 1901 , vol. 34, p. 50
Chemische Berichte, 1901 , vol. 34, p. 4817
反应条件
1: 83 percent / aluminium chloride / benzene / 0.5 h / Heating 2: 99 percent / potassium carbonate / acetone / 4 h / Heating View Scheme
参考文献
Carvalho, Christopher F.; Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1613 - 1620
反应条件
1: 83 percent / aluminium chloride / benzene / 0.5 h / Heating 2: 34 percent / nitric acid, acetic acid / 4 h / 15 - 16 °C / further nitration agents 3: 97 percent / potassium carbonate / dimethylformamide / 14 h / Ambient temperature 4: 1.) hydrogen / 1.) palladized charcoal / 1.) ethanol, 18 h View Scheme
参考文献
Carvalho, Christopher F.; Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1613 - 1620
反应条件
hydrogen iodide 3.5 h; Heating;
参考文献
Brittain, Judith M.; Mare, Peter B. D. de la; Newman, Paul A.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1981 , p. 32 - 41
反应条件
hydrogen iodide in water Heating; Title compound not separated from byproducts;
参考文献
Roush, William R.; Neitz, R. Jeffrey
Journal of Organic Chemistry, 2004 , vol. 69, # 15 p. 4906 - 4912
参考文献
Kohn; Weissberg
Monatshefte fuer Chemie, 1924 , vol. 45, p. 303
反应条件
1: 83 percent / aluminium chloride / benzene / 0.5 h / Heating 2: 22 percent / nitric acid, acetic acid / 4 h / 15 - 16 °C / further nitration agents 3: potassium carbonate / dimethylformamide / Ambient temperature 4: 16 percent / potassium carbonate, copper(II) oxide / 16 h / 140 °C View Scheme
参考文献
Carvalho, Christopher F.; Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1613 - 1620
参考文献
Auwers; Burrows
Chemische Berichte, 1899 , vol. 32, p. 3041
