2-氯甲基咪唑并[1,2-a]嘧啶合成路线 （共 7 条）
反应条件
in ethylene glycol dimethyl ether 48 h; Heating;
参考文献
Roubaud, Christine; Vanelle, Patrice; Maldonado, Jose; Crozet, Michel P.
Tetrahedron, 1995 , vol. 51, # 35 p. 9643 - 9656
反应条件
in ethylene glycol dimethyl ether T=20 - 80°C; 23 h; Heating / reflux;
参考文献
PFIZER INC.
Patent: WO2004/74270 A2, 2004 ;
Location in patent: Page 341 ;
反应条件
in ethylene glycol dimethyl ether 48 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 40, # 5 p. 1170 - 1176
反应条件
Tetra-n-butyl-ammonium 2-nitropropanate in water; toluene 24 h; Ambient temperatureIrradiation;
参考文献
Roubaud, Christine; Vanelle, Patrice; Maldonado, Jose; Crozet, Michel P.
Tetrahedron, 1995 , vol. 51, # 35 p. 9643 - 9656
反应条件
tetrabutylammomium bromide; lithium 1.) ethanol, 2.) toluene, water, RT, irradiation, 24 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Roubaud, Christine; Vanelle, Patrice; Maldonado, Jose; Crozet, Michel P.
Tetrahedron, 1995 , vol. 51, # 35 p. 9643 - 9656
反应条件
Tetra-n-butyl-ammonium 2-nitropropanate in water; toluene 24 h; Ambient temperatureIrradiation;
参考文献
Tetrahedron, , vol. 51, # 35 p. 9643 - 9656
反应条件
tetrabutylammomium bromide; lithium 1.) ethanol, 2.) toluene, water, RT, irradiation, 24 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 51, # 35 p. 9643 - 9656
