3-氨基 苯并呋喃-2-甲酸甲酯合成路线 （共 5 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C; 12 h; Heating / reflux;
参考文献
Suh, Jeehee; Yi, Kyu Yang; Lee, Yun-Suk; Kim, Eunhee; Yum, Eul Kgun; Yoo, Sung-Eun
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 22 p. 6362 - 6365
反应条件
sodium hydride in dimethyl sulfoxide T=25°C; Cyclization; 0.166667 h;
参考文献
Warner-Lambert Company
Patent: US5679683 A1, 1997 ;
反应条件
potassium carbonate in acetone 4 h; Heating / reflux;
参考文献
ATHERSYS, INC.
Patent: WO2006/14647 A2, 2006 ;
Location in patent: Page/Page column 51 ;
WO 2006/014647 A2
反应条件
1: 100 percent / K2CO3 / acetone / 24 h / 25 °C 2: 56 percent / NaH / dimethylsulfoxide / 0.17 h / 25 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 26 p. 5464 - 5474
反应条件
1: 47 percent / 8 h / 135 - 170 °C 2: 93 percent / oxalyl chloride; DMF / 1,2-dichloro-ethane / 1 h / Heating View Scheme
参考文献
Showalter, H. D. Hollis; Bridges, Alexander J.; Zhou, Hairong; Sercel, Anthony D.; McMichael, Amy; Fry, David W.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5464 - 5474
