2,4-二羟基苯基乙醛酸乙酯合成路线 （共 4 条）
反应条件
1: recorcinol With ethylmagnesium bromide in diethyl ether
T=20°C; 0.333333 h;
2: oxalyl dichloride in toluene
T=20°C; 15 h;
3: ethanol in toluene
T=20°C; 1 h;
参考文献
BAYER PHARMACEUTICALS CORPORATION
Patent: WO2005/14566 A1, 2005 ;
Location in patent: Page/Page column 62-63 ;
参考文献
Arnoldi; Merlini; Scaglioni
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 1 p. 75 - 77
反应条件
diethyl ether
Einleiten von Clorwasserstoff und Behandeln des Reaktionsprodukts mit heissem Wasser;
参考文献
Hunsberger; Amstutz
Journal of the American Chemical Society, 1948 , vol. 70, p. 671,673
反应条件
sodium hydroxide in ethanol; water
参考文献
Arnoldi; Merlini; Scaglioni
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 1 p. 75 - 77
