2-甲基-3-戊基环戊-2-烯-1-酮合成路线 （共 7 条）
反应条件
sulfuric acid in methanol
T=0°C; 1.7 h;
参考文献
Hiyama, Tamejiro; Shinoda, Masaki; Saimoto, Hiroyuki; Nozaki, Hitosi
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 9 p. 2747 - 2758
反应条件
1: diethyl ether; tetrahydrofuran / 0.25 h / -78 °C
2: n-BuLi / hexane; tetrahydrofuran / 1 h / Ambient temperature; other α-hydroxy epoxides
View Scheme
参考文献
Doris, Eric; Dechoux, Luc; Mioskowski, Charles
Journal of the American Chemical Society, 1995 , vol. 117, # 51 p. 12700 - 12704
反应条件
1: diethyl ether; tetrahydrofuran / 0.25 h / -78 °C
2: n-BuLi / hexane; tetrahydrofuran / 1 h / Ambient temperature; other α-hydroxy epoxides
View Scheme
参考文献
Doris, Eric; Dechoux, Luc; Mioskowski, Charles
Journal of the American Chemical Society, 1995 , vol. 117, # 51 p. 12700 - 12704
反应条件
hydrogen bromide
T=100°C; 9 h;
参考文献
Hiyama, Tamejiro; Shinoda, Masaki; Tsukanaka, Masao; Nozaki, Hitosi
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 4 p. 1010 - 1014
反应条件
trifluoroacetic acid
Ambient temperature;
参考文献
Hiyama, Tamejiro; Shinoda, Masaki; Tsukanaka, Masao; Nozaki, Hitosi
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 4 p. 1010 - 1014
反应条件
1: 1.) butyllithium / 1.) THF, hexane, -78 deg, 70 min., 2.) THF, hexane, RT, 30 min.
2: 58 percent / sulfuric acid / methanol / 1.7 h / 0 °C
View Scheme
参考文献
Hiyama, Tamejiro; Shinoda, Masaki; Saimoto, Hiroyuki; Nozaki, Hitosi
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 9 p. 2747 - 2758
反应条件
in toluene
P=45600 Torr; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Billington, David C.; Bladon, Peter; Helps, I. Malcolm; Pauson, Peter L.; Thomson, William; Willison, Debra
Journal of Chemical Research, Miniprint, 1988 , # 10 p. 2601 - 2623
