6,7-二甲氧基-1(3h)-异苯并呋喃酮合成路线 (共 82 条)
反应条件
toluene-4-sulfonic acid in dichloromethane 48 h; Ambient temperature;
参考文献
Archiv der Pharmazie, , vol. 325, # 7 p. 425 - 431
反应条件
sodium hydroxide T=50°C;
参考文献
Justus Liebigs Annalen der Chemie, , vol. 301, p. 356
反应条件
1: trifluoroacetic acid / 5 h / Ambient temperature 2: 1) n-butyllithium / 1) ether, ice-water cooling, 1 h, 2) dry ice-acetone bath View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 21 p. 3653 - 3657
反应条件
n-butyllithium 1) ether, ice-water cooling, 1 h, 2) dry ice-acetone bath; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 48, # 21 p. 3653 - 3657
反应条件
Yield given. Multistep reaction;
参考文献
Australian Journal of Chemistry, , vol. 34, # 2 p. 383 - 395
参考文献
Journal of Organic Chemistry, , vol. 19, p. 666,668
反应条件
sodium hydroxide folgend Ansaeuern;
参考文献
Chemische Berichte, , vol. 62, p. 2565
Bulletin de la Societe Chimique de France, , vol. <5> 1, p. 674
反应条件
chloro-trimethyl-silane; Pd(OAc)2*PPh3; potassium carbonate in toluene T=140°C; Carbonylation; cyclization; 24 h;
参考文献
Journal of Organic Chemistry, , vol. 64, # 18 p. 6583 - 6596
反应条件
urea beim Schmelzen;
参考文献
Archiv der Pharmazie (Weinheim, Germany), , vol. 241, p. 268
反应条件
n-butyllithium; carbon dioxide 1.) THF, -78 deg C, 1 min; 2.) THF, 10 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 51, # 9 p. 2489 - 2496