(8S,9S,10S,13R,14S,17R)-10,13-二甲基-17-[(2R)-6-甲基庚烷-2-基]-6,7,8,9,11,12,14,15,16,17-十氢环戊烯并[a]菲-3-酮合成路线 （共 6 条）
566-91-6(8S,9S,10S,13R,14S,17R)-10,13-二甲基-17-[(2R)-6-甲基庚烷-2-基]-6,7,8,9,11,12,14,15,16,17-十氢环戊烯并[a]菲-3-酮
→
反应条件
(Ph)2SiH2; zinc(II) chloride; tetrakis(triphenylphosphine) palladium(0) in chloroform 1 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Keinan, Ehud; Greenspoon, Noam
Journal of the American Chemical Society, 1986 , vol. 108, # 23 p. 7314 - 7325
566-91-6(8S,9S,10S,13R,14S,17R)-10,13-二甲基-17-[(2R)-6-甲基庚烷-2-基]-6,7,8,9,11,12,14,15,16,17-十氢环戊烯并[a]菲-3-酮
→
反应条件
Tl(NO3)3*3H2O in diethylene glycol dimethyl ether 24 h; Ambient temperature;
参考文献
Torrini; Romeo
Farmaco, Edizione Scientifica, 1980 , vol. 35, # 8 p. 681 - 683
566-91-6(8S,9S,10S,13R,14S,17R)-10,13-二甲基-17-[(2R)-6-甲基庚烷-2-基]-6,7,8,9,11,12,14,15,16,17-十氢环戊烯并[a]菲-3-酮
→
反应条件
ethanol; nickel Hydrogenation;
参考文献
Inhoffen; Huang-Minlon
Chemische Berichte, 1938 , vol. 71, p. 1720,1727
Chemische Berichte, 1939 , vol. 72, p. 1686
566-91-6(8S,9S,10S,13R,14S,17R)-10,13-二甲基-17-[(2R)-6-甲基庚烷-2-基]-6,7,8,9,11,12,14,15,16,17-十氢环戊烯并[a]菲-3-酮
→
参考文献
Inhoffen; Huang-Minlon
Chemische Berichte, 1938 , vol. 71, p. 1720,1727
Chemische Berichte, 1939 , vol. 72, p. 1686
566-91-6(8S,9S,10S,13R,14S,17R)-10,13-二甲基-17-[(2R)-6-甲基庚烷-2-基]-6,7,8,9,11,12,14,15,16,17-十氢环戊烯并[a]菲-3-酮
→
反应条件
(Ph)2SiH2; zinc(II) chloride; tetrakis(triphenylphosphine) palladium(0) in chloroform 1 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Keinan, Ehud; Greenspoon, Noam
Journal of the American Chemical Society, 1986 , vol. 108, # 23 p. 7314 - 7325
566-91-6(8S,9S,10S,13R,14S,17R)-10,13-二甲基-17-[(2R)-6-甲基庚烷-2-基]-6,7,8,9,11,12,14,15,16,17-十氢环戊烯并[a]菲-3-酮
→
反应条件
glycine in tetrahydrofuran; water Rearrangement; 20 h; Irradiation;
参考文献
Ishar; Girdhar; Kumar; Rama; Kaur
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 11 p. 1253 - 1261
