5-羟基咪唑并[1,2-a]嘧啶合成路线 （共 4 条）
反应条件
sodium hydroxide in water T=60°C; 96 h; at pH 3.8;
参考文献
Nair, Vasu; Offerman, Rick J.; Turner, Gregory A.
Journal of Organic Chemistry, 1984 , vol. 49, # 21 p. 4021 - 4025
反应条件
in water T=70°C; 48 h; also from chloroacetaldehyde diethylacetal;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 40, # 1 p. 235 - 237
反应条件
N-bromosuccinmide in water 1.) RT, 1 h, 2.) 80 deg C, 1 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 40, # 1 p. 235 - 237
反应条件
sodium hydrogencarbonate; acetic acid 1.) RT, overnight, 2.) RT, 2 h; Yield given. Multistep reaction. Further byproducts given;
参考文献
Sako; Totani; Hirota; Maki
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 1 p. 235 - 237
