1,2-二甲基-5-硝基咪唑合成路线 (共 23 条)
反应条件
acetic acid; dimethyl sulfate in water
反应条件
formic acid 4 h; Reflux;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 5 p. 1274 - 1278
反应条件
tri-n-butyl-tin hydride; 2,2'-azo-bisisobutyronitrile in toluene 5 h; Irradiation; Mechanism;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 1 p. 73 - 80
参考文献
Tetrahedron Letters, , vol. 37, # 11 p. 1901 - 1904
反应条件
sulfuric acid; nitric acid anfangs bei 0grad, dann bei 100grad;
参考文献
Journal of the Chemical Society, , vol. 127, p. 1835
参考文献
Journal of the Chemical Society, , vol. 127, p. 1835
参考文献
Journal of the Chemical Society, , vol. 127, p. 1835
反应条件
1.1: 91 percent / trifluoroacetic acid / dimethylformamide / 12 h / 100 °C 2.1: ozone / CH2Cl2; methanol / 2 h / -78 °C 2.2: 51 percent / dimethyl sulfide / CH2Cl2; methanol / -78 - 20 °C 3.1: sodium borohydride / ethanol; CH2Cl2 / 1 h / 20 °C View Scheme
参考文献
Borch, Richard F.; Liu, Jiwen; Schmidt, James P.; Marakovits, Joseph T.; Joswig, Carolyn; Gipp, Jerry J.; Mulcahy, R. Timothy
Journal of Medicinal Chemistry, 2000 , vol. 43, # 11 p. 2258 - 2265
反应条件
1: 39 percent / SeO2 / 0.08 h / 140 °C 2: 88 percent / ethanol / 24 h / Ambient temperature View Scheme
参考文献
Vanelle; Maldonado; Jentzer; Crozet; Savornin; Delmas; Gasquet; Timon-David
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 4 p. 321 - 325
反应条件
in acetonitrile 48 h; Reflux;
参考文献
Bahnous, Mebarek; Bouraiou, Abdelmalek; Chelghoum, Meryem; Bouacida, Sofiane; Roisnel, Thierry; Smati, Farida; Bentchouala, Chafia; Gros, Philippe C.; Belfaitah, Ali
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1274 - 1278