2-叔-丁氧基-6-氯吡啶合成路线 (共 3 条)
反应条件
in toluene T=80°C; 6 h; Inert atmosphere;
参考文献
Gellrich, Urs; Huang, Jing; Seiche, Wolfgang; Keller, Manfred; Meuwly, Markus; Breit, Bernhard
Journal of the American Chemical Society, 2011 , vol. 133, # 4 p. 964 - 975
反应条件
potassium tert-butylate in toluene T=80°C; Inert atmosphere;
参考文献
WO2013/10453 A1, ;
Page/Page column 144-145 ;
反应条件
1.1: Na; liq. NH3 / 2 h / -78 °C
1.2: 79.8 percent / -78 °C
2.1: 92.5 percent / formic acid / 0.5 h
View Scheme
参考文献
Gellrich, Urs; Huang, Jing; Seiche, Wolfgang; Keller, Manfred; Meuwly, Markus; Breit, Bernhard
Journal of the American Chemical Society, 2011 , vol. 133, # 4 p. 964 - 975