1-(4-甲氧基-苯基)-吡咯烷合成路线 (共 19 条)
反应条件
Cu(I) 3-methylsalicylate; potassium carbonate in dimethyl sulfoxide
T=110°C; 3 h;
参考文献
Farahat, Abdelbasset A.; Boykin, David W.
Tetrahedron Letters, 2014 , vol. 55, # 19 p. 3049 - 3051
反应条件
[{(η5-C5Me5)IrCl}2(μ-Cl)2]; sodium hydrogencarbonate in toluene
T=130°C; 17 h;
参考文献
Fujita, Ken-ichi; Fujii, Takeshi; Komatsubara, Atsuo; Enoki, Youichiro; Yamaguchi, Ryohei
Heterocycles, 2007 , vol. 74, # C p. 673 - 682
反应条件
potassium hydroxide; biphenyl-2-yl-di-tert-butyl-phosphane; 2-(di-t-butylphosphino)biphenyl palladium in toluene
T=90°C; 20 h;
参考文献
Zim, Danilo; Buchwald, Stephen L.
Organic Letters, 2003 , vol. 5, # 14 p. 2413 - 2415
反应条件
copper(l) iodide; potassium carbonate; L-proline in dimethyl sulfoxide
T=65°C; 27 h;
参考文献
Zhang, Hui; Cai, Qian; Ma, Dawei
Journal of Organic Chemistry, 2005 , vol. 70, # 13 p. 5164 - 5173
反应条件
palladium diacetate; caesium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in toluene; tert-butyl alcohol
T=110°C; 24 h;
参考文献
Huang, Xiaohua; Anderson, Kevin W.; Zim, Danilo; Jiang, Lei; Klapars, Artis; Buchwald, Stephen L.
Journal of the American Chemical Society, 2003 , vol. 125, # 22 p. 6653 - 6655
反应条件
potassium carbonate in ethanol; water
T=120°C; P=3878.71 Torr; 0.0833333 h;
参考文献
He, Hongjie; Lin, Qi; Liu, Xiaofeng; Yang, Yongtai; Zhou, Yaming; Jia, Yu; Gao, Xiang
Synthetic Communications, 2012 , vol. 42, # 17 p. 2512 - 2525
反应条件
sodium tetrahydroborate; η6-C6H6BPh3-Rh(COD)+ in dichloromethane; isopropyl alcohol
T=100°C; P=26220 Torr; 30 h;
参考文献
Zhou, Jian-Qiang; Alper, Howard
Journal of Organic Chemistry, 1992 , vol. 57, # 12 p. 3328 - 3331
反应条件
palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; sodium t-butanolate in toluene
T=80°C;
参考文献
Wolfe, John P.; Buchwald, Stephen L.
Journal of Organic Chemistry, 1997 , vol. 62, # 5 p. 1264 - 1267
反应条件
sodium tetrahydroborate; sulfuric acid; water in tetrahydrofuran; methanol
T=10 - 20°C; 1.5 h; Yield given;
参考文献
Verardo, Giancarlo; Dolce, Anna; Toniutti, Nicoletta
Synthesis, 1999 , # 1 p. 74 - 79
反应条件
Shvo catalyst in 1,1-dimethylpropan-1-ol
T=150°C; 24 h;
参考文献
Hollmann, Dirk; Baehn, Sebastian; Tillack, Annegret; Parton, Rudy; Altink, Rinke; Beller, Matthias
Tetrahedron Letters, 2008 , vol. 49, # 40 p. 5742 - 5745