2,3,4,5-四甲基-2-环戊烯酮合成路线 （共 27 条）
反应条件
1: in tetrahydrofuran T=0 - 20°C; 3 h; 2: With acetic acid in tetrahydrofuran 3: With hydrogenchloride; water in diethyl ether 0.5 h;
参考文献
FIRMENICH SA
Patent: WO2008/120175 A1, 2008 ;
Location in patent: Page/Page column 13 ;
反应条件
in diethyl ether 1 h; Heating;
参考文献
Kohl, Franz X.; Jutzi, Peter
Journal of Organometallic Chemistry, 1983 , vol. 243, # 1 p. 119 - 121
反应条件
(i), (ii) I2; Multistep reaction;
参考文献
deVries,L.
Journal of Organic Chemistry, 1960 , vol. 25, p. 1838
参考文献
Davies, Alwyn G.; Goddard, Jeffrey P.; Lusztyk, Ewa; Lusztyk, Janusz
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1982 , p. 737 - 744
反应条件
in anhydrous butyl ether T=-0.16 - 24.84°C;
参考文献
UNIVERSITY OF WARWICK; HABTEMARIAM, Abraha; LIU, Zhe; SOLDEVILA, Joan Josep; PIZARRO, Ana Maria; SADLER, Peter, John
Patent: WO2011/148124 A1, 2011 ;
Location in patent: Page/Page column 37-38 ;
反应条件
lithium 1.) Et2O, 1 h, reflux, 2.) Et2O, 0 deg C, 2 h, then room t.; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Bjoergvinsson, Mar; Halldorsson, Snorri; Arnason, Ingvar; Magull, Joerg; Fenske, Dieter
Journal of Organometallic Chemistry, 1997 , vol. 544, # 2 p. 207 - 215
反应条件
1: LiAlH4 2: p-TsOH / benzene / Ambient temperature 3: 1) BuLi, tetramethylethylenediamine / 1) hexane, room temp., 15 h; 2) Et2O, reflux, 3 d View Scheme
参考文献
Courtot, P.; Pichon, R.; Salaun, J. Y.; Toupet, L.
Canadian Journal of Chemistry, 1991 , vol. 69, # 4 p. 661 - 672
反应条件
lithium aluminium tetrahydride; sulfuric acid Heating;
参考文献
New Journal of Chemistry, , vol. 30, # 1 p. 77 - 92
反应条件
1.1: lithium aluminium hydride / diethyl ether / 2 h 1.2: 37 percent / hydrochloric acid; air / diethyl ether; H2O / 16 h 2.1: n-butyllithium / petroleum ether / 16 h / 0 - 20 °C 2.2: 67 percent / petroleum ether; tetrahydrofuran / 16 h View Scheme
参考文献
Beagley; Davies; Adams; White
Canadian Journal of Chemistry, 2001 , vol. 79, # 5-6 p. 731 - 741
反应条件
in diethyl ether Ambient temperature; Title compound not separated from byproducts;
参考文献
Bensley, Dennis M.; Mintz, Eric A.; Sussangkarn, Susan J.
Journal of Organic Chemistry, 1988 , vol. 53, # 18 p. 4417 - 4419
