N-[10-(乙氧羰基氨基)癸基]氨基甲酸乙酯合成路线 （共 4 条）
反应条件
sodium hydroxide; benzene
参考文献
Laakso; Reynolds
Journal of the American Chemical Society, 1957 , vol. 79, p. 5717,5718
反应条件
triethylamine in water; acetonitrile
T=45°C; 1 h;
参考文献
Sattler, Johann H.; Fuchs, Michael; Tauber, Katharina; Mutti, Francesco G.; Faber, Kurt; Pfeffer, Jan; Haas, Thomas; Kroutil, Wolfgang
Angewandte Chemie - International Edition, 2012 , vol. 51, # 36 p. 9156 - 9159
Angew. Chem., 2012 , vol. 124, # 36 p. 9290 - 9293
反应条件
1: 1,10-dihydroxydecane With [3H]-L-Alanine; L-alanine dehydrogenase; ω-transaminase from Chromobacterium violaceum; alcohol dehydrogenase from Bacillus stearothermophilus; pyridoxal 5'-phosphate; nicotinamide adenine dinucleotide; ammonium chloride; sodium hydroxide in ethylene glycol dimethyl ether; water
T=25°C; pH=8.5; 20 h; Enzymatic reaction;
2: O-carbethoxy-N-hydroxysuccinimide With triethylamine in water; acetonitrile
T=45°C; 1 h;
参考文献
Sattler, Johann H.; Fuchs, Michael; Tauber, Katharina; Mutti, Francesco G.; Faber, Kurt; Pfeffer, Jan; Haas, Thomas; Kroutil, Wolfgang
Angewandte Chemie - International Edition, 2012 , vol. 51, # 36 p. 9156 - 9159
Angew. Chem., 2012 , vol. 124, # 36 p. 9290 - 9293
反应条件
1: nicotinamide adenine dinucleotide; pyridoxal 5'-phosphate; [3H]-L-Alanine; ammonium chloride; L-alanine dehydrogenase; alcohol dehydrogenase from Bacillus stearothermophilus; ω-transaminase from Chromobacterium violaceum; sodium hydroxide / water; ethylene glycol dimethyl ether / 20 h / 25 °C / pH 8.5 / |Enzymatic reaction
2: triethylamine / water; acetonitrile / 1 h / 45 °C
View Scheme
参考文献
Sattler, Johann H.; Fuchs, Michael; Tauber, Katharina; Mutti, Francesco G.; Faber, Kurt; Pfeffer, Jan; Haas, Thomas; Kroutil, Wolfgang
Angewandte Chemie - International Edition, 2012 , vol. 51, # 36 p. 9156 - 9159
Angew. Chem., 2012 , vol. 124, # 36 p. 9290 - 9293
