2-(1-乙氧基亚乙基)丙二腈合成路线

参考文献

Mizuhara, Tsukasa; Kato, Takayuki; Hirai, Atsushi; Kurihara, Hideki; Shimada, Yasuhiro; Taniguchi, Masahiko; Maeta, Hideki; Togami, Hiroaki; Shimura, Kazuya; Matsuoka, Masao; Okazaki, Shiho; Takeuchi, Tomoki; Ohno, Hiroaki; Oishi, Shinya; Fujii, Nobutaka
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 16 p. 4557 - 4561

5417-82-32-(1-乙氧基亚乙基)丙二腈

101080-17-55-氨基-1,3-二甲基-1H-吡唑-4-甲酰胺

参考文献

Cheng; Robins
Journal of Organic Chemistry, 1956 , vol. 21, p. 1240,1242

5417-82-32-(1-乙氧基亚乙基)丙二腈

5453-07-63-氨基-5-甲基-1H-吡唑-4-甲腈

参考文献

Heald, Robert; Price, Stephen; Safina, Brian; Savy, Pascal Pierre Alexandre; Seward, Eileen Mary; Sutherlin, Daniel P.; Waszkowycz, Bohdan
Patent: US2012/202785 A1, 2012 ;
Location in patent: Page/Page column 259 ;

124-42-5盐酸乙脒+

5417-82-32-(1-乙氧基亚乙基)丙二腈

34684-87-24-氨基-5-氰基-2,6-二甲基嘧啶

参考文献

Bennett, Lawrence R.; Blankley, C. John; Fleming, Robert W.; Smith, Ronald D.; Tessman, Deirdre K.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 4 p. 382 - 389

143-37-3乙脒碱+

5417-82-32-(1-乙氧基亚乙基)丙二腈

34684-87-24-氨基-5-氰基-2,6-二甲基嘧啶

参考文献

Huber; Hoelscher
Chemische Berichte, 1938 , vol. 71, p. 87,99

141-52-6乙醇钠+

143-37-3乙脒碱+

5417-82-32-(1-乙氧基亚乙基)丙二腈

34684-87-24-氨基-5-氰基-2,6-二甲基嘧啶

参考文献

Huber; Hoelscher
Chemische Berichte, 1938 , vol. 71, p. 87,99

5417-82-32-(1-乙氧基亚乙基)丙二腈

162702-04-7N-(4-氰基-3-甲基-1,2-噻唑-5-基)-3-甲基丁酰胺

参考文献

Theoclitou, Maria-Elena; Aquila, Brian; Block, Michael H.; Brassil, Patrick J.; Castriotta, Lillian; Code, Erin; Collins, Michael P.; Davies, Audrey M.; Deegan, Tracy; Ezhuthachan, Jayachandran; Filla, Sandra; Freed, Ellen; Hu, Haiqing; Huszar, Dennis; Jayaraman, Muthusamy; Lawson, Deborah; Lewis, Paula M; Nadella, Murali V. P.; Oza, Vibha; Padmanilayam, Maniyan; Pontz, Timothy; Ronco, Lucienne; Russell, Daniel; Whitston, David; Zheng, Xiaolan
Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6734 - 6750

5417-82-32-(1-乙氧基亚乙基)丙二腈

162702-06-9N-(4-氰基-3-甲基-1,2-噻唑-5-基)丁酰胺

参考文献

Theoclitou, Maria-Elena; Aquila, Brian; Block, Michael H.; Brassil, Patrick J.; Castriotta, Lillian; Code, Erin; Collins, Michael P.; Davies, Audrey M.; Deegan, Tracy; Ezhuthachan, Jayachandran; Filla, Sandra; Freed, Ellen; Hu, Haiqing; Huszar, Dennis; Jayaraman, Muthusamy; Lawson, Deborah; Lewis, Paula M; Nadella, Murali V. P.; Oza, Vibha; Padmanilayam, Maniyan; Pontz, Timothy; Ronco, Lucienne; Russell, Daniel; Whitston, David; Zheng, Xiaolan
Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6734 - 6750

74-89-5甲胺+

5417-82-32-(1-乙氧基亚乙基)丙二腈

118663-61-9

参考文献

WO2005/40110 A1, ;

Page/Page column 81 ;

6313-33-3甲脒盐酸盐+

5417-82-32-(1-乙氧基亚乙基)丙二腈

76574-44-26-甲基-5-氰基-4-氨基嘧啶

参考文献

Bennett, Lawrence R.; Blankley, C. John; Fleming, Robert W.; Smith, Ronald D.; Tessman, Deirdre K.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 4 p. 382 - 389