4,6-二氯-5-氨基嘧啶合成路线

参考文献

Takeda Pharmaceutical Company Limited
Patent: EP1731523 A1, 2006 ;
Location in patent: Page/Page column 33-34 ;

参考文献

Nemeryuk, M. P.; Sedov, A. L.; Krepelka, I.; Benes, Ya.; Safonova, T. S.
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Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 10 p. 1398 - 1400

5413-85-44,6-二氯-5-氨基嘧啶+

108-91-8环己胺

5449-10-56-氯-N-环己基-嘧啶-4,5-二胺

参考文献

Lambertucci, Catia; Antonini, Ippolito; Buccioni, Michela; Dal Ben, Diego; Kachare, Dhuldeo D.; Volpini, Rosaria; Klotz, Karl-Norbert; Cristalli, Gloria
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 7 p. 2812 - 2822

5413-85-44,6-二氯-5-氨基嘧啶

5449-10-56-氯-N-环己基-嘧啶-4,5-二胺

参考文献

Schering Corporation
Patent: US4076711 A1, 1978 ;

5413-85-44,6-二氯-5-氨基嘧啶+

71-36-3正丁醇

5452-43-76-氯-N4-环戊基嘧啶-4,5-二胺

参考文献

Burroughs Wellcome Co.
Patent: US5039689 A1, 1991 ;

5413-85-44,6-二氯-5-氨基嘧啶+

1003-03-8环戊胺

5452-43-76-氯-N4-环戊基嘧啶-4,5-二胺

参考文献

Kelley, James L.; Morris Bullock; Krochmal, Mark P.; McLean, Ed W.; Linn, James A.; Durcan, Micheal J.; Cooper, Barrett R.
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5413-85-44,6-二氯-5-氨基嘧啶

40829-68-3

参考文献

Regents of the University of Minnesota
Patent: US4916224 A1, 1990 ;

5413-85-44,6-二氯-5-氨基嘧啶+

74497-02-2

41259-65-86-氯-N4-苯基-4,5-嘧啶二胺

参考文献

GREEN CROSS CORPORATION
Patent: US2012/232090 A1, 2012 ;
Location in patent: Page/Page column 20 ;

5413-85-44,6-二氯-5-氨基嘧啶+

109-73-9正丁胺

41259-67-0N4-丁基-6-氯-4,5-嘧啶二胺

参考文献

Biamonte, Marco A.; Shi, Jiandong; Hong, Kevin; Hurst, David C.; Zhang, Lin; Fan, Junhua; Busch, David J.; Karjian, Patricia L.; Maldonado, Angelica A.; Sensintaffar, John L.; Yang, Yong-Ching; Kamal, Adeela; Lough, Rachel E.; Lundgren, Karen; Burrows, Francis J.; Timony, Gregg A.; Boehm, Marcus F.; Kasibhatla, Srinivas R.
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