2-(2-硝基苯氧基)甲苯合成路线 （共 10 条）
参考文献
Higginbottom,R.; Suschitzky,H.
Journal of the Chemical Society, 1962 , p. 2367 - 2370
反应条件
1: ortho-cresol With sodium hydride in N,N-dimethyl-formamide
T=20°C; 1 h; Inert atmosphere;
2: 2-fluoro-1-nitrobenzene in N,N-dimethyl-formamide
T=20 - 50°C; 13 h; Inert atmosphere;
参考文献
Gao, Kai; Yu, Chang-Bin; Li, Wei; Zhou, Yong-Gui; Zhang, Xumu
Chemical Communications, 2011 , vol. 47, # 27 p. 7845 - 7847
反应条件
anhydrous iron chloride; caesium carbonate; potassium iodide; copper(II) oxide; 1,1'-binaphthyl-2,2'-diol in N,N-dimethyl-formamide
T=120°C; 24 h; Inert atmosphere;
参考文献
Wang, Zhe; Fu, Hua; Jiang, Yuyang; Zhao, Yufen
Synlett, 2008 , # 16 p. 2540 - 2546
参考文献
Bayer Aktiengesellschaft
Patent: US5382686 A1, 1995 ;
参考文献
Cook
Journal of the American Chemical Society, 1901 , vol. 23, p. 806
反应条件
copper
T=150 - 160°C;
参考文献
Higginbottom,R.; Suschitzky,H.
Journal of the Chemical Society, 1962 , p. 2367 - 2370
反应条件
potassium hydroxide; water
anschliessendes Erhitzen mit 2-Chlor-1-nitro-benzol auf 200-210grad;
参考文献
Henley
Journal of the Chemical Society, 1930 , p. 1222
反应条件
N-bromosuccinmide; pentachlorobenzoyl chloride in tetrachloromethane
30 h; Heating;
参考文献
Glinka, Ryszard
Polish Journal of Chemistry, 1982 , vol. 56, # 7/8/9 p. 1139 - 1144
反应条件
1: 59.8 percent / N-bromosuccinimide (NBS), benzoyl perchloride / CCl4 / 30 h / Heating
2: 1.) urotropine, 2.) HCl / 1.) chloroform, reflux, 3 h, 2.) methanol, reflux, 2 h
3: 71 percent / pyridine / 24 h
View Scheme
参考文献
Glinka, Ryszard
Polish Journal of Chemistry, 1982 , vol. 56, # 7/8/9 p. 1139 - 1144
反应条件
1: 59.8 percent / N-bromosuccinimide (NBS), benzoyl perchloride / CCl4 / 30 h / Heating
2: 1.) urotropine, 2.) HCl / 1.) chloroform, reflux, 3 h, 2.) methanol, reflux, 2 h
3: 71 percent / pyridine / 24 h
4: 82 percent / H2 / PtO2 / methanol / 30 °C / 7600 Torr
View Scheme
参考文献
Glinka, Ryszard
Polish Journal of Chemistry, 1982 , vol. 56, # 7/8/9 p. 1139 - 1144
