2,2,6-三甲基-4H-1,3-二英-4-酮合成路线 （共 203 条）
反应条件
in anhydrous xylene
Reflux;
参考文献
Razzaghi-Asl, Nima; Firuzi, Omidreza; Hemmateenejad, Bahram; Javidnia, Katayoun; Edraki, Najmeh; Miri, Ramin
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 22 p. 6893 - 6909
反应条件
diisobutylaluminium hydride; toluene-4-sulfonic acid
1.) irradiation, hexane, 24 h; Multistep reaction. Title compound not separated from byproducts;
参考文献
Baldwin, S. W.; Wilkinson, J. M.
Journal of the American Chemical Society, 1980 , vol. 102, # 10 p. 3634 - 3635
反应条件
in xylene
T=150°C; 0.5 h;
参考文献
Clemens, Robert J.; Hyatt, John A.
Journal of Organic Chemistry, 1985 , vol. 50, # 14 p. 2431 - 2435
反应条件
potassium acetate
T=130°C; 0.333333 h; Microwave irradiation;
参考文献
Lacotte, Pierre; Puente, Celine; Ambroise, Yves
ChemMedChem, 2013 , vol. 8, # 1 p. 104 - 111
反应条件
potassium acetate
T=130°C; 0.333333 h; Microwave irradiation;
参考文献
Lacotte, Pierre; Buisson, David-Alexandre; Ambroise, Yves
European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 722 - 727
反应条件
in xylene
T=150°C; 0.5 h;
参考文献
Clemens, Robert J.; Hyatt, John A.
Journal of Organic Chemistry, 1985 , vol. 50, # 14 p. 2431 - 2435
反应条件
in xylene
T=150°C; 0.5 h;
参考文献
Toueg, Julie; Prunet, Joelle
Synlett, 2006 , # 17 p. 2807 - 2811
反应条件
in N,N-dimethyl-formamide
T=125°C; Microwave irradiation;
参考文献
Knapp, John M.; Zhu, Jie S.; Wood, Alex B.; Kurth, Mark J.
ACS Combinatorial Science, 2012 , vol. 14, # 2 p. 85 - 88
参考文献
Sato, Masayuki; Ogasawara, Hiromischi; Kato, Keiko; Sakai, Masako; Kato, Tetsuzo
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4300 - 4305
反应条件
T=110 - 115°C; Product distribution / selectivity;
参考文献
RATIOPHARM GMBH; CHRIST, Jochen; STRIEGEL, Hans-Guenter
Patent: WO2010/136458 A1, 2010 ;
Location in patent: Page/Page column 19 ;
