(6-甲氧基喹啉)-4-羧酸乙酯合成路线 （共 12 条）
参考文献
Pictet; Misner
Chemische Berichte, 1912 , vol. 45, p. 1804
反应条件
1: N2H4+H2O 2: aqueous HCl; aqueous NaNO2 / -10 °C 3: ethanol 4: aqueous HCl View Scheme
参考文献
John
Journal fuer Praktische Chemie (Leipzig), 1930 , vol. <2> 128, p. 201,206
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=55°C;
参考文献
ACTELION PHARMACEUTICALS LTD
Patent: WO2008/78305 A2, 2008 ;
Location in patent: Page/Page column 95 ;
WO 2008/078305 A2
反应条件
ethanol; sulfuric acid
参考文献
John
Journal fuer Praktische Chemie (Leipzig), 1930 , vol. <2> 128, p. 201,206
Full Text Show Details
Thielepape; Fulde
Chemische Berichte, 1939 , vol. 72, p. 1432,1438
参考文献
Hirsch
Monatshefte fuer Chemie, 1896 , vol. 17, p. 336
反应条件
1: SnCl2; concentrated HCl / anschliessendes Behandeln mit wss. NaOH
2: ethanol; concentrated H2SO4
View Scheme
参考文献
Thielepape; Fulde
Chemische Berichte, 1939 , vol. 72, p. 1432,1438
反应条件
1: diethyl ether; sodium ethylate / Behandeln des Reaktionsgemisches mit konz.Schwefelsaeure
2: concentrated H2SO4
3: PCl5; POCl3
4: SnCl2; concentrated HCl / anschliessendes Behandeln mit wss. NaOH
5: ethanol; concentrated H2SO4
View Scheme
参考文献
Thielepape; Fulde
Chemische Berichte, 1939 , vol. 72, p. 1432,1438
反应条件
1: PCl5; POCl3
2: SnCl2; concentrated HCl / anschliessendes Behandeln mit wss. NaOH
3: ethanol; concentrated H2SO4
View Scheme
参考文献
Thielepape; Fulde
Chemische Berichte, 1939 , vol. 72, p. 1432,1438
反应条件
1: concentrated H2SO4
2: PCl5; POCl3
3: SnCl2; concentrated HCl / anschliessendes Behandeln mit wss. NaOH
4: ethanol; concentrated H2SO4
View Scheme
参考文献
Thielepape; Fulde
Chemische Berichte, 1939 , vol. 72, p. 1432,1438
反应条件
1: platinum; aqueous KOH / Hydrogenation
2: ethanol; concentrated H2SO4
View Scheme
参考文献
Thielepape; Fulde
Chemische Berichte, 1939 , vol. 72, p. 1432,1438
