6,6’-二氯-2,2’-联吡啶合成路线 （共 21 条）
反应条件
ethylmagnesium bromide in tetrahydrofuran; diethyl ether
1 h; Ambient temperature;
参考文献
Oae, Shigeru; Kawai, Tsutomu; Furukawa, Naomichi
Phosphorus and Sulfur and the Related Elements, 1987 , vol. 34, p. 123 - 132
反应条件
methylmagnesium bromide in tetrahydrofuran
0.25 h; Ambient temperature;
参考文献
Wakabhayashi; Tanaka; Kubo; Uenishi; Oae
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 12 p. 3848 - 3850
反应条件
phosphorus pentachloride; trichlorophosphate
20 h; Heating;
参考文献
Ogawa, Shojiro; Shiraishi, Shinsaku
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2527 - 2530
反应条件
phosphorus pentachloride; trichlorophosphate in water
20 h; Heating;
参考文献
Yamada, Masaki; Nakamura, Yoshio; Kuroda, Shigeyasu; Shimao, Ichiro
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 9 p. 2710 - 2712
反应条件
methylmagnesium bromide in tetrahydrofuran
0.25 h; Ambient temperature;
参考文献
Wakabhayashi; Tanaka; Kubo; Uenishi; Oae
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 12 p. 3848 - 3850
反应条件
1: 37 percent / potassium hexacyanoferrate(III), NaOH / H2O / 5 °C / T < 5 deg C
2: 11 percent / PCl5, POCl3 / H2O / 20 h / Heating
View Scheme
参考文献
Yamada, Masaki; Nakamura, Yoshio; Kuroda, Shigeyasu; Shimao, Ichiro
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 9 p. 2710 - 2712
反应条件
trichlorophosphate
5 h; Heating;
参考文献
Constable, Edwin C.; Seddon, Kenneth R.
Tetrahedron, 1983 , vol. 39, # 2 p. 291 - 296
反应条件
1: 95 percent / 30percent hydrogen peroxide / acetic acid / 24 h
2: 55 percent / EtMgBr / diethyl ether; tetrahydrofuran / 1 h / Ambient temperature
View Scheme
参考文献
Oae, Shigeru; Kawai, Tsutomu; Furukawa, Naomichi
Phosphorus and Sulfur and the Related Elements, 1987 , vol. 34, p. 123 - 132
反应条件
1: 2.) potassium ferricyanide, NaOH / 1.) 100 deg C, 1 h, 2.) water, 5 deg C
2: 99 percent / PCl5, phosphoryl chloride / 20 h / Heating
View Scheme
参考文献
Ogawa, Shojiro; Shiraishi, Shinsaku
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2527 - 2530
反应条件
phosphorus pentachloride; trichlorophosphate
参考文献
Kao, Hsien-Chang; Wang, Yi-Chun; Wang, Wen-Jwu
Journal of the Chinese Chemical Society, 2012 , vol. 59, # 8 p. 934 - 939
