5-氨基-1-甲基-吡唑-4-甲腈合成路线 （共 27 条）
反应条件
triethylamine in methanol Reflux;
参考文献
RALLIS INDIA LIMITED; PALIMKAR, Sanjay Sambhajirao; PAWAR, Jivan Dhanraj; SANKAR, B; KADAM, Subhash Rajaram; HINDUPUR, Rama Mohan; PRABHU, Venkatesh M.; PATI, Hari Narayan; SUPHALA, Vadiraj Gopinath; MANE, Avinash Sheshrao
Patent: WO2014/2111 A1, 2014 ;
Location in patent: Page/Page column 38 ;
反应条件
in ethanol 1 h; Heating;
参考文献
Harden; Quinn; Scammells
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2892 - 2898
Title/Abstract Full Text View citing articles Show Details
Dooley, Michael J.; Quinn, Ronald J.; Scammells, Peter J.
Australian Journal of Chemistry, 1989 , vol. 42, # 5 p. 747 - 750
反应条件
triethylamine in methanol Reflux;
参考文献
RALLIS INDIA LIMITED; PALIMKAR, Sanjay Sambhajirao; PAWAR, Jivan Dhanraj; SANKAR, B; KADAM, Subhash Rajaram; HINDUPUR, Rama Mohan; PRABHU, Venkatesh M; PATI, Hari Narayan; SUPHALA, Vadiraj Gopinath; MANE, Avinash Sheshrao
Patent: WO2014/2110 A1, 2014 ;
Location in patent: Page/Page column 79; 80 ;
反应条件
trifluoroacetic acid in methanol; toluene 72 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 53, # 2 p. 382 - 386
反应条件
potassium carbonate in N,N-dimethyl-formamide T=100 - 120°C;
参考文献
Paira, Priyankar; Chow, Mun Juinn; Venkatesan, Gopalakrishnan; Kosaraju, Vamsi Krishna; Cheong, Siew Lee; Klotz, Karl-Norbert; Ang, Wee Han; Pastorin, Giorgia
Chemistry - A European Journal, 2013 , vol. 19, # 25 p. 8321 - 8330
反应条件
1: 89 percent / acetonitrile / Ambient temperature 2: 48 percent / trifluoroacetic acid / toluene; methanol / 72 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 2 p. 382 - 386
反应条件
in ethanol 2 h; Heating;
参考文献
Dooley, Michael J.; Quinn, Ronald J.; Scammells, Peter J.
Australian Journal of Chemistry, 1989 , vol. 42, # 5 p. 747 - 750
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 7 p. 1961 - 1966
反应条件
1: With hydrogenchloride; sodium nitrite in water T=0 - 5°C; 2: With urea; copper(l) chloride in water T=0 - 20°C;
参考文献
RALLIS INDIA LIMITED; PALIMKAR, Sanjay Sambhajirao; PAWAR, Jivan Dhanraj; SANKAR, B; KADAM, Subhash Rajaram; HINDUPUR, Rama Mohan; PRABHU, Venkatesh M.; PATI, Hari Narayan; SUPHALA, Vadiraj Gopinath; MANE, Avinash Sheshrao
Patent: WO2014/2111 A1, 2014 ;
Location in patent: Page/Page column 38; 39 ;
反应条件
1: 5-Amino-1-methyl-1H-pyrazole-4-carbonitrile With hydrogenchloride; sodium nitrite in water T=0 - 20°C; 2: urea With copper(l) chloride in water T=0 - 20°C;
参考文献
RALLIS INDIA LIMITED; PALIMKAR, Sanjay Sambhajirao; PAWAR, Jivan Dhanraj; SANKAR, B; KADAM, Subhash Rajaram; HINDUPUR, Rama Mohan; PRABHU, Venkatesh M.; PATI, Hari Narayan; SUPHALA, Vadiraj Gopinath; MANE, Avinash Sheshrao
Patent: WO2014/2109 A1, 2014 ;
Location in patent: Page/Page column 97 ;
