5-溴氨基苯甲酸甲酯合成路线

参考文献

OSI PHARMACEUTICALS, LLC; CREW, Andrew, P.; DONG, Hanqing; FERRARO, Caterina; SHERMAN, Dan; SIU, Kam, W.
Patent: WO2012/74951 A1, 2012 ;
Location in patent: Page/Page column 50-51 ;
WO 2012/074951 A1

77-78-1硫酸二甲酯+

5794-88-72-氨基-5-溴苯甲酸

52727-57-85-溴氨基苯甲酸甲酯

参考文献

Hadida Ruah, Sara S.; Miller, Mark T.; Bear, Brian; McCartney, Jason; Grootenhuis, Peter D. J.
Patent: US2008/9524 A1, 2008 ;
Location in patent: Page/Page column 410 ;

5794-88-72-氨基-5-溴苯甲酸

52727-57-85-溴氨基苯甲酸甲酯

参考文献

Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;

544-92-3氰化亚铜

52727-57-85-溴氨基苯甲酸甲酯

参考文献

PHARMACIA and UPJOHN COMPANY
Patent: WO2004/18414 A2, 2004 ;
Location in patent: Page 136 ;

67-56-1甲醇

52727-57-85-溴氨基苯甲酸甲酯

参考文献

Leiby, Robert W.
Journal of Organic Chemistry, 1985 , vol. 50, # 16 p. 2926 - 2929

134-20-3邻氨基苯甲酸甲酯

52727-57-85-溴氨基苯甲酸甲酯

参考文献

Chaudhuri, Subrata Kumar; Roy, Sanchita; Saha; Bhar, Sanjay
Synthetic Communications, 2007 , vol. 37, # 4 p. 581 - 585

134-20-3邻氨基苯甲酸甲酯

104670-74-82-氨基-3-溴苯甲酸甲酯+

52727-57-85-溴氨基苯甲酸甲酯

参考文献

Roche, Didier; Prasad, Kapa; Repic, Oljan; Blacklock, Thomas J.
Tetrahedron Letters, 2000 , vol. 41, # 13 p. 2083 - 2085

134-20-3邻氨基苯甲酸甲酯

606-00-83,5-二溴邻氨基苯甲酸甲酯+

104670-74-82-氨基-3-溴苯甲酸甲酯+

52727-57-85-溴氨基苯甲酸甲酯

参考文献

Roche, Didier; Prasad, Kapa; Repic, Oljan; Blacklock, Thomas J.
Tetrahedron Letters, 2000 , vol. 41, # 13 p. 2083 - 2085

87-48-95-溴靛红

52727-57-85-溴氨基苯甲酸甲酯

参考文献

BASF Aktiengesellschaft
Patent: US4310677 A1, 1982 ;

67-56-1甲醇+

87-48-95-溴靛红

5794-88-72-氨基-5-溴苯甲酸+

52727-57-85-溴氨基苯甲酸甲酯

参考文献

Reissenweber, Gernot; Mangold, Dietrich
Angewandte Chemie, 1981 , vol. 93, # 10 p. 914 - 915