(7CI,8CI,9CI)-3-甲基-噻唑并[3,2-a]苯并咪唑合成路线 （共 32 条）
反应条件
1: 1.) KOH, triethylbenzylammonium chloride / 1.) DMSO, reflux, 0.5, 2.) THF, dioxane, 60-80 deg C, 3 h
2: 95 percent / KOH, TEBAC / dimethylsulfoxide / 3 h / Heating
View Scheme
参考文献
Popov, I. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995 , vol. 31, # 4 p. 500 - 503
Khimiya Geterotsiklicheskikh Soedinenii, 1995 , # 4 p. 567 - 570
反应条件
triethylamine in methanol
T=20°C; 0.5 h;
参考文献
Doukara, Abdallah Larbi; Mehdid, Mohammed Amine; Djafri, Ayada; Andreoli, Federico; Vanthuyne, Nicolas; Roussel, Christian
Tetrahedron, 2010 , vol. 66, # 10 p. 1852 - 1858
反应条件
18-crown-6 ether; potassium carbonate; potassium iodide in toluene
12 h; Reflux;
参考文献
Beresneva; Belyakov; Abele; Lukevics
Chemistry of Heterocyclic Compounds, 2011 , vol. 46, # 11 p. 1400 - 1404
反应条件
1: reconstructed hydrotalcite / ethanol; water / 0.42 h / 70 °C / 2250.23 - 3000.3 Torr / |Microwave irradiation; |Cooling
2: reconstructed hydrotalcite / ethanol / 0.33 h / 70 °C / |Microwave irradiation; |Cooling
View Scheme
参考文献
Cruz-Gonzalez, Deysi Y.; Gonzalez-Olvera, Rodrigo; Angeles-Beltran, Deyanira; Negron-Silva, Guillermo E.; Santillan, Rosa
Synthesis (Germany), 2013 , vol. 45, # 23 p. 3281 - 3287
参考文献
Chadha,V.K. et al.
Indian Journal of Chemistry, 1969 , vol. 7, p. 769 - 771
参考文献
Ogura,H. et al.
Journal of Heterocyclic Chemistry, 1969 , vol. 6, p. 797 - 802
反应条件
2: polyphosphoric acid
View Scheme
参考文献
Ogura,H. et al.
Journal of Heterocyclic Chemistry, 1969 , vol. 6, p. 797 - 802
参考文献
Krasovskii,A.N.; Kochergin,P.M.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1969 , vol. 5, p. 243 - 245
Khimiya Geterotsiklicheskikh Soedinenii, 1969 , vol. 5, # 2 p. 321 - 324
反应条件
hydrogenchloride
15 h; Heating;
参考文献
Alper,A.E.; Taurins,A.
Canadian Journal of Chemistry, 1967 , vol. 45, p. 2903 - 2912
反应条件
in ethanol
4 h; Heating;
参考文献
Krasovskii,A.N.; Kochergin,P.M.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1969 , vol. 5, p. 243 - 245
Khimiya Geterotsiklicheskikh Soedinenii, 1969 , vol. 5, # 2 p. 321 - 324
