N-苄氧羰基-D-苯丙氨酰胺合成路线 （共 11 条）
反应条件
pyridine; bis-[(trifluoroacetoxy)iodo]benzene in tetrahydrofuran oxidative Hofmann rearrangement;
参考文献
Myers, Adam C.; Kowalski, Jennifer A.; Lipton, Mark A.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 20 p. 5219 - 5222
反应条件
2,4,6-trichloro-1,3,5-triazine in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
SEATTLE GENETICS, INC.
Patent: WO2007/8848 A2, 2007 ;
Location in patent: Page/Page column 147 ;
反应条件
hydrogen; palladium 10 on activated carbon in methanol 16 h;
参考文献
WO2012/61418 A2, ;
Page/Page column 89-90 ;
WO 2012/061418 A2
反应条件
hydrogen; palladium on activated charcoal in N,N-dimethyl-formamide 18 h; Ambient temperature;
参考文献
Ramage, Robert; Hopton, David; Parrott, Maxwell J.; Richardson, Reginald S.; Kenner, George W.; Moore, Geoffrey A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 461 - 470
反应条件
hydrogen; palladium on activated charcoal in acetic acid
参考文献
Journal of the Chemical Society. Perkin transactions 1, , vol. 5, p. 555 - 566
反应条件
alcalase cross-linked enzyme aggregates T=50°C; 48 h; Molecular sieveEnzymatic reaction;
参考文献
Nuijens, Timo; Piva, Elena; Kruijtzer, John A. W.; Rijkers, Dirk T. S.; Liskamp, Rob M. J.; Quaedflieg, Peter J. L. M.
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 7 p. 1039 - 1044
反应条件
hydrogen; palladium 10 on activated carbon in methanol 16 h;
参考文献
WO2012/61418 A2, ;
Page/Page column 89-90 ;
WO 2012/061418 A2
反应条件
hydrogen; palladium 10 on activated carbon in methanol 16 h;
参考文献
WO2012/61418 A2, ;
Page/Page column 89-90 ;
WO 2012/061418 A2
反应条件
alcalase cross-linked enzyme aggregates T=50°C; 48 h; Molecular sieveEnzymatic reaction;
参考文献
Nuijens, Timo; Piva, Elena; Kruijtzer, John A. W.; Rijkers, Dirk T. S.; Liskamp, Rob M. J.; Quaedflieg, Peter J. L. M.
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 7 p. 1039 - 1044
反应条件
alcalase cross-linked enzyme aggregates
T=50°C; 48 h; Molecular sieveEnzymatic reaction;
参考文献
Nuijens, Timo; Piva, Elena; Kruijtzer, John A. W.; Rijkers, Dirk T. S.; Liskamp, Rob M. J.; Quaedflieg, Peter J. L. M.
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 7 p. 1039 - 1044
