in water
T=25°C; spectroscopic method, variation of the pH: the rate constant for the thiol-disulfide exchange (kSH) and for the thiolate ion-disulfide exchange (Ks-) as well as the activation energy were determined; Rate constant;
参考文献
Ozawa, Toshihiko; Hanaki, Akira
Chemical & Pharmaceutical Bulletin, 1981 , vol. 29, # 4 p. 1101 - 1105
1: 22 percent / pyridine / 48 h / 0 °C
2: 39 percent / H2O / 0.17 h / Heating
View Scheme
参考文献
Al-Zaidi, Shakir M.R.; Crilley, Martine M. L.; Stoodley, Richard J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 2259 - 2266
1: 23 percent / pyridine / 48 h / 0 °C
2: 53 percent / PCl5 / CH2Cl2 / 0.08 h
3: 54 percent / Et3N / CH2Cl2 / 12 h
4: 50 percent / potassium t-butoxide / tetrahydrofuran / 1 h / 0 °C
View Scheme
参考文献
Al-Zaidi, Shakir M.R.; Crilley, Martine M. L.; Stoodley, Richard J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 2259 - 2266
1: 23 percent / pyridine / 48 h / 0 °C
2: 53 percent / PCl5 / CH2Cl2 / 0.08 h
3: 59 percent / Et3N / CH2Cl2 / 12 h
4: 22 percent / potassium t-butoxide / tetrahydrofuran / 1 h / 0 °C
View Scheme
参考文献
Al-Zaidi, Shakir M.R.; Crilley, Martine M. L.; Stoodley, Richard J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 2259 - 2266
1: 23 percent / pyridine / 48 h / 0 °C
2: 53 percent / PCl5 / CH2Cl2 / 0.08 h
3: 59 percent / Et3N / CH2Cl2 / 12 h
4: 22 percent / potassium t-butoxide / tetrahydrofuran / 1 h / 0 °C
5: 40 percent / tetrahydrofuran / 1 h
View Scheme
参考文献
Al-Zaidi, Shakir M.R.; Crilley, Martine M. L.; Stoodley, Richard J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 2259 - 2266
1: 1M NaOH / dioxane / 3 h
2: DCC / CH2Cl2 / 1 h / 0 °C
3: 87 percent / HBr / acetic acid / 0.5 h
4: 92 percent / Et3N / CH2Cl2 / 18 h
5: 65 percent / NaH / dimethylformamide / 1 h / 0 °C
6: 46 percent / 1M hydrochloric acid / acetone / 1 h
View Scheme
参考文献
Al-Zaidi, Shakir M.R.; Crilley, Martine M. L.; Stoodley, Richard J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 2259 - 2266
