α-乙酰基-γ-丁内酯合成路线 （共 116 条）
反应条件
sodium hydroxide in ethanol; water T=-5 - 0°C; 50 h;
参考文献
Cornish Christopher A.; Warren, Stuart
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2585 - 2598
反应条件
sodium hydroxide 1.) water, EtOH, 0 deg C, 30 min, 2.) 0 - 5 deg C, 72 h; Yield given. Multistep reaction;
参考文献
Henkel Corporation
Patent: US5183908 A1, 1993 ;
反应条件
1: tetrahydrofuran-2-one With lithium hexamethyldisilazane in tetrahydrofuran T=-78°C; 0.25 h; Inert atmosphere; 2: acetic anhydride in tetrahydrofuran T=-78°C; 1 h; Inert atmosphere;
参考文献
Schroeder, Sybrin P.; Taylor, Nicholas J.; Jackson, Paula; Franckevicius, Vilius
Organic Letters, 2013 , vol. 15, # 14 p. 3778 - 3781
反应条件
lithium diisopropyl amide in tetrahydrofuran T=-78°C;
参考文献
Sato, Yosuke; Fukuda, Hayato; Tomizawa, Masaki; Masaki, Tomohito; Shibuya, Masatoshi; Kanoh, Naoki; Iwabuchi, Yoshiharu
Heterocycles, 2010 , vol. 81, # 10 p. 2239 - 2246
反应条件
aluminium trichloride; Trioxane in methanol Dehydration; Heating;
参考文献
Tyrlik, Stanislaw K.; Szerszen, Dorota; Olejnik, Marian; Danikiewicz, Witold
Carbohydrate Research, 1999 , vol. 315, # 3-4 p. 268 - 272
反应条件
18-crown-6 ether 1.) THF, RT, 15 min, 2.) THF, RT, 3 h; Yield given. Multistep reaction;
参考文献
Jedlinski, Zbigniew; Kowalczuk, Marek; Kurcok, Piotr; Grzegorzek, Miroslaw; Ermel, Jolanta
Journal of Organic Chemistry, 1987 , vol. 52, # 20 p. 4601 - 4602
参考文献
Matsukawa
Yakugaku Zasshi, 1942 , vol. 62, p. 417,443;dtsch.Ref.S.122,125
Chem.Abstr., 1951 , p. 4724
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Willimann; Schinz
Helvetica Chimica Acta, 1952 , vol. 35, p. 2401,2405
Full Text Show Details
Knunjanz; Tschelinzew; Ossetrowa
Doklady Akademii Nauk SSSR, 1934 , p. I 314
Chem. Zentralbl., 1934 , vol. 105, # II p. 2381
参考文献
Wang, Wei; Zhang, Sheng-Wan; Li, Mei-Ping; Ren, Ying-Yu
Chemical Papers, 2013 , vol. 67, # 6 p. 624 - 630
反应条件
water T=25°C; Rate constantMechanism;
参考文献
Naringrekar; Stella
Journal of Pharmaceutical Sciences, 1990 , vol. 79, # 2 p. 138 - 146
参考文献
Matsukawa
Yakugaku Zasshi, 1942 , vol. 62, p. 417,443;dtsch.Ref.S.122,125
Chem.Abstr., 1951 , p. 4724
