4,4-二硝基-2,2-联吡啶 N,N-二氧化物合成路线 （共 17 条）
反应条件
sulfuric acid; nitric acid T=95 - 100°C; 20 h;
参考文献
Kavanagh, Paul; Leech, Donal
Tetrahedron Letters, 2004 , vol. 45, # 1 p. 121 - 123
反应条件
1: 94 percent / aq. H2O2; AcOH / 13 h / 70 - 80 °C 2: 52 percent / HNO3; H2SO4/SO3 / 8 h / 100 °C View Scheme
参考文献
Carlson, Brenden; Phelan, Gregory D.; Kaminsky, Werner; Dalton, Larry; Jiang, Xuezhong; Liu, Sen; Jen, Alex K.-Y.
Journal of the American Chemical Society, 2002 , vol. 124, # 47 p. 14162 - 14172
反应条件
1: PCl3 / 60 °C 2: H2O; KMnO4; H2SO4 View Scheme
参考文献
Haginiwa
Yakugaku Zasshi, 1955 , vol. 75, p. 733,735
Chem.Abstr., 1956 , p. 3436
反应条件
hydrazine hydrate; palladium on activated charcoal in ethanol Reduction; 8 h; Heating;
参考文献
Maury; Guegana; Renouard; Hilton; Dupau; Sandon; Toupet; Le Bozec
New Journal of Chemistry, 2001 , vol. 25, # 12 p. 1553 - 1566
反应条件
phosphorus trichoride 21 h; Heating;
参考文献
Ten Brink, Gerd-Jan; Arends, Isabel W. C. E.; Hoogenraad, Marcel; Verspui, Goeran; Sheldon, Roger A.
Advanced Synthesis and Catalysis, 2003 , vol. 345, # 4 p. 497 - 505
反应条件
phosphorus trichoride in acetonitrile 1) reflux, 1.75 h, 2) room temperature, overnight;
参考文献
Wenkert, David; Woodward, R. B.
Journal of Organic Chemistry, 1983 , vol. 48, # 3 p. 283 - 289
反应条件
1.1: acetyl-bromide / acetic acid / 4 h / 100 °C 2.1: phosphorus tribromide / acetonitrile / 4 h / Reflux 3.1: sodium carbonate / water; toluene / 0.25 h / Inert atmosphere 3.2: 14 h / Reflux View Scheme
参考文献
Han, Won-Sik; Han, Jung-Kyu; Kim, Hyun-Young; Choi, Mi Jin; Kang, Yong-Soo; Pac, Chyongjin; Kang, Sang Ook
Inorganic Chemistry, 2011 , vol. 50, # 8 p. 3271 - 3280
反应条件
1: 67 percent / NaOMe / 5 h / 30 - 35 °C 2: 60 percent / PCl3 / CHCl3 / 5 h / Heating View Scheme
参考文献
Maerker; Case
Journal of the American Chemical Society, 1958 , vol. 80, p. 2745,2747
反应条件
acetyl-bromide in acetic acid T=130°C; 10 h;
参考文献
Heterocycles, , vol. 75, # 1 p. 57 - 64
反应条件
phosphorus trichoride T=60°C;
参考文献
Zhang, Dong; Dufek, Eric J.; Clennan, Edward L.
Journal of Organic Chemistry, 2006 , vol. 71, # 1 p. 315 - 319
