3,7-二甲基-2,6-辛二烯腈合成路线 （共 33 条）
反应条件
sulfuric acid T=0°C; 6 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kron, A. A.; Burdin, E. A.; Novikov, N. A.; Aul'chenko, I. S.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, p. 1901 - 1904
Zhurnal Organicheskoi Khimii, 1990 , vol. 27, # 10 p. 2149 - 2154
反应条件
potassium hydroxide; phosphoric acid 1.) toluene, 110 deg C, 8 h, 2.) methanol, 20 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Kron, A. A.; Burdin, E. A.; Novikov, N. A.; Aul'chenko, I. S.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, p. 1901 - 1904
Zhurnal Organicheskoi Khimii, 1990 , vol. 27, # 10 p. 2149 - 2154
参考文献
Tiemann
Chemische Berichte, 1898 , vol. 31, p. 827
Full Text Show Details
Tiemann; Semmler
Chemische Berichte, 1893 , vol. 26, p. 2720
参考文献
Tiemann
Chemische Berichte, 1898 , vol. 31, p. 827
Full Text Show Details
Tiemann; Semmler
Chemische Berichte, 1893 , vol. 26, p. 2720
反应条件
sulfuric acid in nitromethane
T=0°C; Cyclization; 0.5 h; Title compound not separated from byproducts.;
参考文献
Jansen, Frans Jos H. M.; Lugtenburg, Johan
European Journal of Organic Chemistry, 2000 , # 5 p. 829 - 836
反应条件
phosphoric acid in toluene
T=110°C; 8 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kron, A. A.; Burdin, E. A.; Novikov, N. A.; Aul'chenko, I. S.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, p. 1901 - 1904
Zhurnal Organicheskoi Khimii, 1990 , vol. 27, # 10 p. 2149 - 2154
反应条件
Zeolite β in pentane
2 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Luzina; Tatarova; Korchagina; Salakhutdinov; Barkhash
Russian Journal of Nondestructive Testing, 1997 , vol. 33, # 2 p. 183 - 193
反应条件
sulfuric acid
T=0°C; 6 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kron, A. A.; Burdin, E. A.; Novikov, N. A.; Aul'chenko, I. S.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, p. 1901 - 1904
Zhurnal Organicheskoi Khimii, 1990 , vol. 27, # 10 p. 2149 - 2154
反应条件
1: With 1,1,3,3-tetramethyldisiloxane; titanium (IV) isopropoxide in toluene
T=60°C; 24 h; Inert atmosphere;
2: With hydrogenchloride; water in toluene
T=20°C; Inert atmosphere; Overall yield = 95 percent; Optical yield = 2 percent de;
参考文献
Laval, Stephane; Dayoub, Wissam; Pehlivan, Leyla; Metay, Estelle; Favre-Reguillon, Alain; Delbrayelle, Dominique; Mignani, Gerard; Lemaire, Marc
Tetrahedron, 2014 , vol. 70, # 4 p. 975 - 983
反应条件
1: With anhydrous iron chloride; tri-isobutyl aluminium
T=10 - 25°C; 17 h;
2: With sodium hydroxide; water
T=-10 - 20°C;
参考文献
GIVAUDAN SA
Patent: WO2006/66437 A1, 2006 ;
Location in patent: Page/Page column 1; 2 ;
