3,7-二甲基-2,6-辛二烯腈合成路线 （共 33 条）
反应条件
bismuth trifluoromethanesulphonate; methanecarbohydroxamic acid in acetonitrile 14 h; Reflux;
参考文献
Sridhar, Madabhushi; Reddy, Mallu Kishore Kumar; Sairam, Vangipuram Venkata; Raveendra, Jillella; Godala, Kondal Reddy; Narsaiah, Chinthala; Ramanaiah, Beeram China; Reddy, Cirandur Suresh
Tetrahedron Letters, 2012 , vol. 53, # 27 p. 3421 - 3424
反应条件
dimethyl dithiocarbonate; triethylamine in 1,4-dioxane T=90°C;
参考文献
Khan, Taukeer Ahmad; Peruncheralathan, Saravanan; Ila, Hiriyakkanavar; Junjappa, Hiriyakkanavar
Synlett, 2004 , # 11 p. 2019 - 2021
反应条件
1: cyanomethyl-phosphonic acid diethyl ester With sodium hydride in tetrahydrofuran T=0 - 20°C; Metallation; 2: 6-methyl-hept-5-en-2-one in tetrahydrofuran T=20°C; Condensation; Wittig reaction; 2 h; Further stages.;
参考文献
Jansen, Frans Jos H. M.; Lugtenburg, Johan
European Journal of Organic Chemistry, 2000 , # 5 p. 829 - 836
反应条件
potassium hydroxide 4 h; Heating;
参考文献
Valla, Alain; Cartier, Dominique; Laurent, Alain; Valla, Benoist; Labia, Roger; Potier, Pierre
Synthetic Communications, 2003 , vol. 33, # 7 p. 1195 - 1201
反应条件
1.1: 70 percent / diethyl ether / 1 h / 0 °C 2.1: NaH / tetrahydrofuran / 0 - 20 °C 2.2: 89.4 percent / tetrahydrofuran / 2 h / 20 °C View Scheme
参考文献
Jansen, Frans Jos H. M.; Lugtenburg, Johan
European Journal of Organic Chemistry, 2000 , # 5 p. 829 - 836
反应条件
1.1: n-BuLi / tetrahydrofuran / 0.25 h / -70 °C 1.2: 82 percent / tetrahydrofuran / -70 - 20 °C 2.1: 70 percent / diethyl ether / 1 h / 0 °C 3.1: NaH / tetrahydrofuran / 0 - 20 °C 3.2: 89.4 percent / tetrahydrofuran / 2 h / 20 °C View Scheme
参考文献
Jansen, Frans Jos H. M.; Lugtenburg, Johan
European Journal of Organic Chemistry, 2000 , # 5 p. 829 - 836
反应条件
piperidine; benzene unter Entfernen des entstehenden Wassers und anschliessenden Erhitzen in Gegenwart von Kupfer;
参考文献
Sarytschewa et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 1189,1191;engl.Ausg.S.1159,1161
参考文献
Chemische Berichte, , vol. 31, p. 827
Chemische Berichte, , vol. 26, p. 2720
反应条件
sodium tetrahydroborate; RuCl3 monohydrate in 1-methyl-pyrrolidin-2-one; water T=0°C; 1 h; chemoselective reaction;
参考文献
Babler, James H.; Ziemke, David W.; Hamer, Robert M.
Tetrahedron Letters, 2013 , vol. 54, # 13 p. 1754 - 1757
反应条件
magnesium in methanol
参考文献
Profitt,J.A. et al.
Journal of Organic Chemistry, 1975 , vol. 40, # 1 p. 127 - 128
